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GenomicsExpression data from THP1-wt and THP1-NTR+ cells with LSD1 inhibitor (OG86), Nitroreductase NfsB (NTR) prodrug and negative control
Expression data from THP1-wt and THP1-NTR+ cells with LSD1 inhibitor (OG86), Nitroreductase NfsB (NTR) prodrug and negative control
PRJNA650534 | ENA
Transcriptomicsntr-Transcriptomic study of a thioredoxin reductase knock-out mutant.
rs04-02_ntr - ntr - Thioredoxins are small redox proteins implicated in crucial pathways of cell life. They are reduced by a conserved flavoprotein named NADPH-dependent thioredoxin reductase (NTR). In order to give an insight into the functions of the NTR/thioredoxin pathway in Arabidopsis, we have...
ORGANISM(S): Arabidopsis thaliana 
2007-06-19 | E-GEOD-7998 | biostudies-arrayexpress
TranscriptomicsExpression data from THP1-wt and THP1-NTR+ cells with LSD1 inhibitor (OG86), Nitroreductase NfsB (NTR) prodrug and negative control
The Nitroreductase NfsB (NTR) prodrug of an LSD1 inhibitor is inactive in wild-type THP1 cells, but the prodrug gets activated in the LSD1 inhibitor by the NTR in NTR-expressing THP1 cells (THP1-NTR+). Cell-type specific inhibition of LSD1 in THP1-NTR+ cells with a NTR prodrug is shown with the expr...
ORGANISM(S): Homo sapiens 
2020-08-04 | GSE155640 | GEO
Transcriptomicsntr-Transcriptomic study of a thioredoxin reductase knock-out mutant.
rs04-02_ntr - ntr - Thioredoxins are small redox proteins implicated in crucial pathways of cell life. They are reduced by a conserved flavoprotein named NADPH-dependent thioredoxin reductase (NTR). In order to give an insight into the functions of the NTR/thioredoxin pathway in Arabidopsis, we have...
ORGANISM(S): Arabidopsis thaliana 
2007-06-20 | GSE7998 | GEO
TranscriptomicsEffect of neurotrophin p75 receptor (p75NTR) on angiogenesis
Neurotrophins (NTs) promotes angiogenesis and EC survival, via tropomyosin kinase trkA and trkB receptors. A different p75NTR receptor of NTs, which belongs to the TNF-alfa receptor superfamily, is not or scarcely expressed by endothelial cells (EC) and endothelial progenitor cells (EPC) under basal...
ORGANISM(S): Mus musculus 
2010-06-25 | E-GEOD-9910 | biostudies-arrayexpress
TranscriptomicsBasonuclin-1 modulates epithelial plasticity and TGF-β1-induced loss of epithelial cell integrity [NIAC-NTR]
TGF-b1-stimulation induces an epithelial dedifferentiation-process, throughout which epithelial cell sheets disintegrate and gradually switch into fibroblastic-appearing cells (EMT-like transition). The purpose of these profiles was to identify differentially expressed genes that are regulated trans...
ORGANISM(S): Mus musculus 
2014-03-01 | GSE54716 | GEO
ProteomicsVirotrap-based interactome analysis of a NTR protein
Ribosome profiling has revealed translation outside of canonical coding sequences (CDSs) including translation of short upstream ORFs, long non-coding RNAs, overlapping ORFs, ORFs in UTRs or ORFs in alternative reading frames. Studies combining mass spectrometry, ribosome profiling and CRISPR-based ...
ORGANISM(S): Homo sapiens (Human) 
2022-07-12 | PXD030216 | Pride
Virotrap Protein-protein interaction Lc-ms/ms 
UnknownFine-tuning of amino sugar homeostasis by EIIA(Ntr) in Salmonella Typhimurium.
Not available
S-EPMC5024086 | biostudies-literature
UnknownNeurotrophin receptor p75(NTR) mediates Huntington's disease-associated synaptic and memory dysfunction.
Not available
S-EPMC4191006 | biostudies-literature
UnknownAssociation of p75(NTR) and α9β1 integrin modulates NGF-dependent cellular responses.
Not available
S-EPMC4409011 | biostudies-literature
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