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GenomicsExamination of hepatic SREBP-2 binding using ChIP-Seq
Sterol regulatory element binding proteins (SREBPs) are key transcriptional regulators of lipid metabolism. To define functional differences between the three mammalian SREBPs we are using genome-wide ChIP-seq with isoform-specific antibodies and chromatin from select tissues of mice challenged with...
ORGANISM(S): Mus musculus 
2011-03-22 | E-GEOD-28082 | biostudies-arrayexpress
TranscriptomicsIntegrated omics studies delineate the formation and dynamics of lipid droplets in Rhodococcus opacus PD630 for biofuel feedstock
Purpose: To delineate mechanisms underlying lipid storage in LDs, we compared the transcriptomes of cells cultivated under three lipid-accumulating conditions. Methods: PD630 mRNA profiles of 3 different conditions (normal condition and LDs acculation conditions) were generated by deep sequencing, u...
ORGANISM(S): Rhodococcus opacus 
2013-11-04 | E-GEOD-42381 | biostudies-arrayexpress
MetabolomicsThe putative ceramide-conjugation protein Cwh43 regulates G0 quiescence, nutrient metabolism and lipid homeostasis in fission yeast (Lipidome assay)
Cellular nutrient states control whether cells proliferate, or whether they enter or exit quiescence. Here, we report characterizations of fission yeast temperature-sensitive (ts) mutants of the evolutionarily conserved transmembrane protein, Cwh43, and explore its relevance to utilization of glucos...
2018-08-21 | MTBLS578 | MetaboLights
MetabolomicsThe putative ceramide-conjugation protein Cwh43 regulates G0 quiescence, nutrient metabolism and lipid homeostasis in fission yeast (Metabolome assay)
Cellular nutrient states control whether cells proliferate, or whether they enter or exit quiescence. Here, we report characterizations of fission yeast temperature-sensitive (ts) mutants of the evolutionarily conserved transmembrane protein, Cwh43, and explore its relevance to utilization of glucos...
2018-08-17 | MTBLS577 | MetaboLights
ProteomicsMapping the lipid droplet proteome by using proximity labeling in ccRCC cell lines
Comprehensive understanding of the lipid droplet (LD) proteome in ccRCC cells is lacking. In this study, we employed TurboID, an engineered biotin ligase with great efficiency for enzyme-catalyzed proximity labeling, to map the spatial proteome of LDs in ccRCC cells.
ORGANISM(S): Homo sapiens (Human) 
2025-08-28 | PXD048174 | Pride
Lipid droplet Turboid Proximity labeling Clear cell renal cell carcinoma Hilpda 
GenomicsAF6 promotes lipid droplet fusion and aggravates MASH via C/EBPβ–CIDEA axis
AF6 promotes lipid droplet fusion and aggravates MASH via C/EBPβ–CIDEA axis
PRJNA1307434 | ENA
UnknownNuclear-lipid-droplet proteome: carboxylesterase as a nuclear lipase involved in lipid-droplet homeostasis.
Not available
S-EPMC8010399 | biostudies-literature
GenomicsPPARa regulates ER-lipid droplet protein Calsyntenin-3b to promote ketogenesis in hepatocytes
PPARa regulates ER-lipid droplet protein Calsyntenin-3b to promote ketogenesis in hepatocytes
PRJNA1224734 | ENA
UnknownAge-dependent nuclear lipid droplet deposition is a cellular hallmark of aging in Caenorhabditis elegans.
Not available
S-EPMC10086520 | biostudies-literature
UnknownNuclear Lipid Droplet Birth during Replicative Stress.
Not available
S-EPMC9105094 | biostudies-literature
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