Nuclear speckle

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Effects of the long noncoding RNA Malat1 on gene expression [MoEx-1_0-st]

Malat1 is an abundant long noncoding RNA that localizes to nuclear bodies known as nuclear speckles, which contain a distinct set of pre-mRNA processing factors. Previous in vitro studies have demonstrated that Malat1 interacts with pre-mRNA splicing factors, including the serine- and arginine-rich ...

ORGANISM(S): Mus musculus

2012-06-24 | E-GEOD-37706 | biostudies-arrayexpress

Effects of the long noncoding RNA Malat1 on gene expression [Mouse430_2]

ORGANISM(S): Mus musculus

2012-06-24 | E-GEOD-37705 | biostudies-arrayexpress

The Nuclear-retained non-coding RNA MALAT1 regulates alternative splicing by modulating SR splicing factor phosphorylation

Alternative splicing (AS) of pre-mRNA is utilized by higher eukaryotes to achieve increased transcriptome and proteomic complexity. The serine/arginine (SR) splicing factors regulate tissue- or cell type-specific AS in a concentration and phosphorylation dependent manner. However, the mechanisms tha...

ORGANISM(S): Homo sapiens

2010-09-01 | E-GEOD-22963 | biostudies-arrayexpress

Coordination of nuclear RNA processing by speckle-localized kinase TAOK2

PRJNA1418735 | ENA

CTCF/RAD21 organize the ground state of chromatin-nuclear speckle association

PRJNA1041777 | ENA

p53 transcription factor mediates nuclear speckle association of target genes

PRJNA645124 | ENA

Phosphorylation controls mRNA retention via nuclear speckle cohesion - APEX2-seq

PRJNA1005653 | ENA

CTCF/cohesin organize the ground state of chromatin-nuclear speckle association [CUT&RUN]

PRJNA1041450 | ENA