Nucleic acid delivery

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With L-glutamine supplemented with 10% fetal bovine serum (FBS) (Gibco) and 1% penicillin-streptomycin (10,000 units/mL penicillin and 10 mg/mL streptomycin) (Gibco). (1)
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CHEBI ID

CHEBI:15891 (5)
CHEBI:16543 (4)
CHEBI:18295 (4)
CHEBI:18257 (4)
CHEBI:17562 (4)
CHEBI:17748 (4)
CHEBI:15428 (4)
CHEBI:18243 (4)
CHEBI:17821 (4)
CHEBI:18211 (4)
CHEBI:15354 (4)
CHEBI:17775 (4)
CHEBI:18344 (4)
CHEBI:36206 (3)
CHEBI:40521 (3)
CHEBI:17521 (3)
CHEBI:6032 (3)
CHEBI:72998 (3)
CHEBI:16450 (3)
CHEBI:15611 (3)
CHEBI:49033 (3)
CHEBI:25094 (3)
CHEBI:18237 (3)
CHEBI:16040 (3)
CHEBI:22660 (3)
CHEBI:22653 (3)
CHEBI:28300 (3)
CHEBI:17533 (3)
CHEBI:16708 (3)
CHEBI:73527 (3)

Metabolite Name

Ornithine (3)
Dopamine (3)
Taurine (3)
11-beta-Hydroxyandrosterone-3-glucuronide (2)
Dopamine (2)
(R)-3-hydroxybutyrylcarnitine (2)
19,20-DiHDPA (2)
6-Hydroxypentadecanedioic acid (2)
8-Amino-7-oxononanoic acid (2)
P-cresol sulfate (2)
3-Methylcrotonylglycine (2)
12-Ketodeoxycholic acid (2)
N1-Methyl-2-pyridone-5-carboxamide (2)
Miglitol (2)
Glycine (2)
12,13-DiHOME (2)
L-Alanine (2)
Salbutamol (2)
Capryloylglycine (2)
Furfural (2)
Trigonelline (2)
Ecgonine (2)
Thymine (2)
N1,N12-Diacetylspermine (2)
Citrulline (2)
Propionic acid (2)
Isobutyric acid (2)
4-Pyridoxic acid (2)
7-Methylguanine (2)
Tryptamine (2)

First Public Date

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2014 (5)
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2023 (2)
2021 (2)
2022 (1)
2019 (1)
2016 (1)

Classification

viruses (1)
bacteria (1)

Study type

Transcription profiling by array (623)
RNA-seq of coding RNA (95)
Methylation profiling by array (27)
RNA-seq of coding RNA from single cells (21)
RNA-seq of non coding RNA (20)
ChIP-seq (14)
Unknown experiment type (13)
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Other (11)
Genotyping by array (7)
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DNA-seq (5)
Methylation profiling by high throughput sequencing (5)
MicroRNA profiling by array (4)
Cell line - One-color microarray (3)
MicroRNA profiling by high throughput sequencing (3)
ChIP-chip by tiling array (2)
Animal - High-throughput sequencing (2)
Bisulfite-seq (2)
ATAC-seq (2)
RIP-seq (2)
Proteomic profiling by array (2)
Transcription profiling by SAGE (1)
Animal - Two-color microarray (1)
Differential (1)
MeDIP-seq (1)
RIP-chip by array (1)
Animal - One-color microarray (1)

Release Date

2025 (183)
2022 (162)
2023 (155)
2024 (150)
2014 (148)
2013 (130)
2015 (127)
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2016 (109)
2012 (105)
2011 (100)
2010 (98)
2019 (91)
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2018 (68)
2017 (66)
2026 (52)
2008 (51)
2009 (50)
2007 (13)
2005 (8)
2006 (6)
2004 (4)
2003 (1)

Lab affiliation

CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China. (2)
1Gavin Herbert Eye Institute –Brunson Center for Translational Vision Research, Department of Ophthalmology and Visual Sciences, University of California Irvine, Irvine, CA 92697, USA 2Department of Physiology and Biophysics, University of California Irvine, Irvine, CA 92697, USA 3Department of Chemistry, University of California Irvine, Irvine, CA 92697, USA 4Department of Molecular Biology and Biochemistry, University of California Irvine, Irvine, CA 92697, USA (1)
Astrazeneca (1)
Biochemistry and Molecular Genetics, Hematology and Oncology, Department of Medicine, Northwestern University, USA (1)
Buchmann Institute for Molecular Life Sciences, Goethe University Frankfurt am Main, Germany (1)
Department of Biochemistry, The University of Western Ontario, London, Ontario, Canada. 2 Bioinformatic Solutions Inc., Waterloo, Ontario, Canada. Department of Chemistry, The University of Western Ontario, London, Ontario, Canada. (1)
Department of Chemistry Michigan State University (1)
Department of Pharmaceutical Sciences Oregon State University College of Pharmacy Portland, OR 97301 USA (1)
Department of Pharmaceutical Sciences, University at Buffalo and NYS Center of Excellence in Bioinformatics and Life Sciences, University at Buffalo, USA (1)
Department of Pharmaceutical Sciences, University at Buffalo, US (1)
Experimental Systems Immunology, Max Planck Institute of Biochemistry, Martinsried, Germany. (1)
Institute of Biomedical Engineering and Technology, Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200062, P.R. China (1)
Mass Spectrometry for Biology Unit, CNRS USR2000, Institut Pasteur, CNRS, 28 rue du Dr Roux, Paris 75015, France. (1)
Pharmocology Asc Professor Emory University (1)
Research Service (R&D22) VA Portland Health Care System 3710 SW US Veterans Hospital Rd. Portland, OR 97239 USA (1)

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Multifunctional nucleic acids for tumor cell treatment.

Not available

S-EPMC3962646 | biostudies-literature

Experimental Model Systems Used in the Preclinical Development of Nucleic Acid Therapeutics.

Not available

S-EPMC10457615 | biostudies-literature

Polymeric vehicles for nucleic acid delivery.

Not available

S-EPMC7736472 | biostudies-literature

Ionizable polymeric micelles (IPMs) for efficient siRNA delivery

Lipid nanoparticles (LNPs) are widely used for nucleic acid delivery but face challenges like limited targeting and accelerated blood clearance. We design three ionizable oligo-mers (IOs) that, with PLA-PEG, form Ionizable Polymeric Micelles (IPMs), a potential siRNA delivery system, which can achie...

ORGANISM(S): Mus musculus (Mouse)

2024-11-21 | PXD057444 | Pride