Sort   by:  
 Page size 
ProteomicsThe nucleolus functions as the compartment for histone 1 H2B protein degradation
Histones are the main components in chromatin organization, and the protein levels of histones significantly affect chromatin assembly. However, how the protein levels of histones are regulated, especially whether and how histones are degraded, is largely unclear. Here, we found that histone H2B is ...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD023415 | Pride
H2b   protein degradation   nucleolus   polyubiquitination 
TranscriptomicsComparative genomic hybridization of human genomic DNA and nucleolus-associated DNA in HeLa cell line.
The aim of the experiment was to identify nucleolus-associated chromosomal domains. HeLa exp samples represent DNA from isolated nucleoli, whereas HeLa ref samples total genomic DNA of HeLa cells. "exp" samples were Cy5 labeled and hybridized together with Cy3-labeled "ref" sampl...
ORGANISM(S): Homo sapiens 
2010-10-11 | E-MEXP-2403 | biostudies-arrayexpress
ProteomicsRECQ5 mediates pre-rRNA processing in nucleolus
explore the biological function of RECQ5 in nucleolus
ORGANISM(S): Homo Sapiens 
2024-11-19 | PXD058022 |
TranscriptomicsTwo-cell developmental block is due to the lack of cytoplasmic lattices in mouse antral oocytes
Mammalian oogenesis is a complex mechanism entailing the maturation of primordial follicles into preovulatory follicles followed by the release of antral oocytes. In the ovary, the antral compartment consists of two populations of oocytes whose main difference regards the ability to resume meiosis a...
ORGANISM(S): Mus musculus 
2013-02-04 | E-GEOD-34671 | biostudies-arrayexpress
OtherMapping nucleolus-associated chromatin interactions by nucleolus-Hi-C reveals repression network
Nucleolus plays a key role in organizing global nuclear structure and facilitating gene regulation, but the three dimensional information within the nucleolus associated chromatins are still unknown, so here we development the Nucleolus Hi-C (NHi-C) experimental technique, which combines the nucleol...
ORGANISM(S): Homo sapiens 
2021-02-01 | GSE90003 | GEO
ProteomicsBMAL1 associates with NOP58 in the nucleolus and contributes to pre-rRNA processing
The transcription factor BMAL1 is a core element of the circadian clock that contributes to cyclic control of genes transcribed by RNA polymerase II. By using biochemical cellular fractionation and immunofluorescence analyses we reveal a previously uncharacterized nucleolar localization for BMAL1. W...
ORGANISM(S): Mus musculus (Mouse) 
2020-08-25 | PXD018946 | Pride
Bmal1 interactome Nucleolus Circadian clock Ribosome biogenesis 
GenomicsMapping and engineering RNA-driven architecture of the multiphase nucleolus
Mapping and engineering RNA-driven architecture of the multiphase nucleolus
PRJNA1257945 | ENA
GenomicsMapping and engineering RNA-driven architecture of the multiphase nucleolus
Mapping and engineering RNA-driven architecture of the multiphase nucleolus
PRJNA1257780 | ENA
GenomicsThe nucleolar granular component mediates genome-nucleolus interactions and establishes their repressive chromatin states
The nucleolar granular component mediates genome-nucleolus interactions and establishes their repressive chromatin states
PRJNA1128154 | ENA
GenomicsGenome-wide maps of nucleolus interactions in human cells using 4xAP3 DamID
Genome-wide maps of nucleolus interactions in human cells using 4xAP3 DamID
PRJNA625198 | ENA
Sort   by:  
 Page size