Nup214 - OmicsDI

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School of Basic Medical Sciences, Chongqing Medical University (2)
1Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC 27599, USA. 2Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC 27599, USA. 3Biological and Biomedical Sciences Program, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. (1)
Amsterdam UMC, Vrije Universiteit Amsterdam, Medical Oncology, Cancer Center Amsterdam, OncoProteomics Laboratory, Amsterdam, Netherlands (1)
Centre for Medical Genetics, Institute of Reproductive Genetics, University of Münster, Vesaliusweg 12-14, 48149 Münster, Germany. (1)
Centre for Medical Genetics, Institute of Reproductive Genetics, University of Münster, Vesaliusweg 12-14, 48149, Münster, Germany. (1)
DCG, Hematology, Cardiff University, UK (1)
School of Basic Medical Sciences, Chongqing Medical Universityqing Medical Universityic Medical Sciences, Chongqing Medical University (1)
University of Melbourne, Melbourne, Australia (1)
VIRO unit, de Duve Institute, Université Catholique de Louvain, Brussels, 1200, Belgium (1)

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DEK/NUP214 SILAC interactormics analysis

Among most of leukemogenic fusion proteins the aberrant localization that the translocation partners are forced in when compared to their wt counterparts contributes to leukemogenesis most likely by a sequester of interaction partners. The aim was to disclose the role of localization of DEK/NUP214...

ORGANISM(S): Homo sapiens (Human)

2022-10-14 | PXD031885 | Pride

XPO1-dependency of DEK::NUP214 leukemia sensitizes against eltanexor

PRJNA1126303 | ENA

Cooperation between TLX1 and the NUP214-ABL1/STAT5 signaling in T-cell acute lymphoblastic leukemia

PRJNA397010 | ENA

NUP214 in Leukemia: It's More than Transport.

Not available

S-EPMC6356203 | biostudies-literature

XPO1-dependency of DEK::NUP214 leukemia sensitizes against eltanexor

We aimed to investigate the role of XPO1 in this rare leukemia subtype. ChIP-sequencing was performed for XPO1 and NUP214 (as surrogate for DEK::NUP214 protein), and found co-occupancy of both proteins in putative DEK::NUP214 target genes.

ORGANISM(S): Homo sapiens

2025-03-28 | GSE270396 | GEO

Functional dissection of RanBP2 and Nup88/Nup214 subcomplex in nucleocytoplasmic transport

PRJNA550143 | ENA

Targeted CRM1-inhibition perturbs leukemogenic NUP214 fusion proteins and exerts anti-cancer effects in leukemia cell lines with NUP214 rearrangements.

Not available

S-EPMC7486696 | biostudies-literature

NUP214 Rearrangements in Leukemia Patients: A Case Series From a Single Institution.

Not available

S-EPMC10961622 | biostudies-literature

NUP214 fusion genes in acute leukemias: genetic characterization of rare cases.

Not available