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MetabolomicsUntargeted metabolomic profiling of nutrient supplementation during Agaricus bisporus cultivation

This study investigated stage-specific metabolomic responses of Agaricus bisporus compost to a commercial nutrient supplement (MC) compared with an unsupplemented control (CK). Untargeted UHPLC–MS/MS metabolomics was performed across different cultivation stages to characterize metabolite changes...

2026-09-06 | MTBLS15556 | MetaboLights
MetabolomicsNutrient depletion and systems-wide metabolic shifting in polymer-producing wastewater bacterium

Inorganic nutrient deficiency stimulates polymer synthesis in bacterial producers relevant to wastewater treatment and biotechnology, but the metabolic mechanisms are poorly understood. Here, using a quantitative multi-omics analysis of the wastewater isolate Comamonas testosteroni durin...

2026-09-09 | MTBLS12449 | MetaboLights
MetabolomicsHost autophagy mediates organ wasting and nutrient mobilization for tumor growth
During tumor growth-when nutrient and anabolic demands are high-autophagy supports tumor metabolism and growth through lysosomal organelle turnover and nutrient recycling. Ras-driven tumors additionally invoke non-autonomous autophagy in the microenvironment to support tumor growth, in part through ...
2021-09-24 | MTBLS2771 | MetaboLights
MetabolomicsRumen Fluid Metabolomic Profiles of Postpartum Tan Ewes Fed Diets with Different Nutrient Levels
This study investigated the rumen fluid metabolomic profiles of postpartum Tan ewes fed diets formulated to meet 100%, 115%, or 130% of nutrient requirements. Rumen fluid samples were collected from six ewes per dietary group at each ewe’s individual first estrus.
2026-07-21 | MTBLS15108 | MetaboLights
MetabolomicsRumen Fluid Metabolomic Profiles of Postpartum Tan Ewes Fed Diets with Different Nutrient Levels
This study investigated the rumen fluid metabolomic profiles of postpartum Tan ewes fed diets formulated to meet 100%, 115%, or 130% of nutrient requirements. Rumen fluid samples were collected from six ewes per dietary group at each ewe’s individual first estrus.
2026-07-21 | MTBLS15107 | MetaboLights
MetabolomicsBacterial extracellular vesicles as recyclable nutrient reservoirs

Bacterial extracellular vesicles (EVs) are known to mediate intercellular communication, virulence, and immune modulation. Here we show that bacteria can utilise EVs also as recyclable nutrient reservoirs. Using Bacillus cereus as a model organism, we demonstrate that EVs exhibit distin...

2026-02-18 | MTBLS13260 | MetaboLights
MetabolomicsMulti-Omics Reveals that Alkaline Mineral Complex Enhances Nutrient Digestion–Absorption and Gut Health

This study, conducted under a high-concentrate finishing context, used an integrated multi-omics approach to evaluate the effects of an Alkaline Mineral Complex (AMC) on jejunal digestion–absorption and gut health in beef cattle. The results showed that AMC alleviated mucosal pathological injury ...

2026-07-14 | MTBLS13175 | MetaboLights
MetabolomicsThe Toxoplasma micropore mediates endocytosis for selective nutrient salvage from host cell compartments

Apicomplexan parasite growth and replication relies on nutrient acquisition from host cells, in which intracellular multiplication occurs, yet the mechanisms that underlie the nutrient salvage remain elusive. Numerous ultrastructural studies have documented a plasma membrane invagination with a d...

2023-04-19 | MTBLS7006 | MetaboLights
MetabolomicsMetabolism links nutrient stress and harmful algal bloom formation

Four species of phytoplankton representing important bloom-forming species from three globally important phyla (Bacillariophyta, Haptophyta, and Ochrophyte) were cultured in this study. These species include the cosmopolitan diatom Chaetoceros affinis CCMP159 (isolated from Great South B...

2024-02-28 | MTBLS1807 | MetaboLights
MetabolomicsGain-of-function genetic screens in human cells identify SLC transporters overcoming environmental nutrient restrictions

Solute carrier (SLC) transporters control fluxes of nutrients and metabolites across membranes and thereby represent a critical interface between the microenvironment and cellular and subcellular metabolism. Because of substantial functional overlap, the interplay and relative contributions of SL...

2022-09-20 | MTBLS4268 | MetaboLights
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