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GenomicsDecoding genome-wide GadEWX transcriptional regulatory networks reveals a multifaceted cellular response to acid stress in Escherichia coli [ChIP-seq]
The response to acid stress is a fundamental process in bacteria. Three transcription factors, GadE, GadW, and GadX (GadEWX) are known to play a critical role in the transcriptional regulation of glutamate-dependent acid resistance (GDAR) system in Escherichia coli K-12 MG1655. However, the regulato...
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
2015-08-11 | E-GEOD-66441 | biostudies-arrayexpress
TranscriptomicsDecoding genome-wide GadEWX transcriptional regulatory networks reveals a multifaceted cellular response to acid stress in Escherichia coli [RNA-seq]
The response to acid stress is a fundamental process in bacteria. Three transcription factors, GadE, GadW, and GadX (GadEWX) are known to play a critical role in the transcriptional regulation of glutamate-dependent acid resistance (GDAR) system in Escherichia coli K-12 MG1655. However, the regulato...
ORGANISM(S): Escherichia coli 
2015-08-11 | E-GEOD-66481 | biostudies-arrayexpress
UnknownSubconductance gating and voltage sensitivity of sarcoplasmic reticulum K(+) channels: a modeling approach.
Not available
S-EPMC4623209 | biostudies-literature
UnknownEngineering proteinase K using machine learning and synthetic genes.
Not available
S-EPMC1847811 | biostudies-literature
ProteomicsRNF43 G659fs is an oncogenic colorectal cancer mutation and sensitizes tumor cells to PI3K/mTOR inhibition
Fang L, Ford-Roshon D, Russo M, O'Brien C, Xiong X, Gurjao C, Grandclaudon M, Raghavan S, Corsello SM, Carr SA, Udeshi ND, Berstler J, Sicinska E, Ng K, Giannakis M. 2022. The RNF43_p.G659fs mutation occurs frequently in colorectal cancer, but its function remains poorly understood and there are no ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-04-29 | MSV000089343 | MassIVE
GenomicsDecoding genome-wide GadEWX transcriptional regulatory networks reveals a multifaceted cellular response to acid stress in Escherichia coli
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
2015-08-11 | E-GEOD-66482 | biostudies-arrayexpress
UnknownGlycolytic and gluconeogenic growth of Escherichia coli O157:H7 (EDL933) and E. coli K-12 (MG1655) in the mouse intestine.
Not available
S-EPMC355998 | biostudies-literature
TranscriptomicsExpression Profiling E. Coli Evolved on Glucose Minimal Media
mRNA sequencing was performed on E. coli evolved at 37C on M9 Minimal Media with Glucose Growth of evolved E. coli was characterized under the same conditions as the evolution and compared to the wild type parent strain
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
2014-12-03 | E-GEOD-61327 | biostudies-arrayexpress
TranscriptomicsResistance to PI3K/mTOR inhibitor PF-04691502 in KRAS mutant colorectal cancer models reveals a sensitivity to combination with EGFR inhibition
We explored potential bypass mechanisms to PI3K/mTOR-directed therapy in KRAS mutant CRC models, utilizing genetically engineered mouse models (GEMM) to generate acquired resistance to the targeted dual PI3K/mTOR small molecule inhibitor PF-04691502. Transcriptomic analysis revealed a dynamic stem-l...
ORGANISM(S): Mus musculus 
2014-08-31 | E-MTAB-2510 | biostudies-arrayexpress
UnknownUse of adaptive laboratory evolution to discover key mutations enabling rapid growth of Escherichia coli K-12 MG1655 on glucose minimal medium.
Not available
S-EPMC4272732 | biostudies-literature
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