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TranscriptomicsDietary folate depletion and repletion in A/J and C57BL/6J mice
Defects in homocysteine and folate metabolism are associated with increased risks for neural tube and congenital heart defects, cardiovascular disease and stroke, cancers, and neurodegeneration. In many but not all cases, dietary supplementation with folate significantly reduces the severity and in...
ORGANISM(S): Mus musculus 
2008-08-27 | E-GEOD-9242 | biostudies-arrayexpress
TranscriptomicsDietary folate depletion and repletion in C57BL/6J mice, ApoE knockout mice, and choline supplemented C57BL/6J mice
Defects in homocysteine and folate metabolism are associated with increased risks for neural tube and congenital heart defects, cardiovascular disease and stroke, cancers, and neurodegeneration. In many but not all cases, dietary supplementation with folate significantly reduces the severity and in...
ORGANISM(S): Mus musculus 
2008-08-27 | E-GEOD-9243 | biostudies-arrayexpress
TranscriptomicsExpression data from the PVD and OLL neurons in C. elegans
Nociceptive neurons develop a complex dendritic arbor to sense noxious stimuli, which enables animals to react to environmental insults and perform self-protective behaviours. The genetic programs controlling neuronal dendritic morphogenesis are poorly understood. In C. elegans, the PVD sensory neur...
ORGANISM(S): Caenorhabditis elegans 
2010-07-08 | E-GEOD-21162 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse skin from K6/ODC animals response to folate deficient diets reveals folate deficiency enhances arsenic effects
We demonstrate that expression of key markers of keratinocyte differentiation is suppressed by exposure to sodium arsenite. Folate deficiency exacerbates this effect. In addition, cancer-related cell movement genes, and growth and proliferation genes are altered. Several redox-sensitive transcrip...
ORGANISM(S): Mus musculus 
2008-06-16 | E-GEOD-8733 | biostudies-arrayexpress
UnknownStat2 loss leads to cytokine-independent, cell-mediated lethality in LPS-induced sepsis.
Not available
S-EPMC3666758 | biostudies-literature
TranscriptomicsPapillary thyroid cancer cell lines treated with Y15
3 papillary thyroid cancer cell lines were compared, treated with Y15 to untreated. 1 million cells of each papillary thyroid cell line (TPC1, K1, BCPAP) were plated, treated 24 hours later with 10uM Y15, and collected 24 hours later by trypsinization.
ORGANISM(S): Homo sapiens 
2014-03-06 | E-GEOD-55603 | biostudies-arrayexpress
TranscriptomicsThe small molecule compound Y15 and PF04554878 in TT cells
Global gene expression in TT cells treated with FAK inhibitors TT cells were untreated and treated with Y15 small molecule FAK inhibitor at 10 microM or another FAK inhibitor PF04554878 at 10microM, total RNA was isolated and gene expression was analyzed using Illumina chips
ORGANISM(S): Homo sapiens 
2015-07-03 | E-GEOD-55619 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse Dll3 and Notch1 homozygous mutant embryos to investigate craniofacial malformations of human birth defects
Mutations in the Notch1 receptor and delta-like 3 (Dll3) ligand cause global disruptions in axial segmental patterning. Genetic interactions between members of the notch pathway have previously been shown to cause patterning defects not observed in single gene disruptions. We examined Dll3-Notch1 ...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-8027 | biostudies-arrayexpress
UnknownRepotrectinib in <i>ROS1</i> Fusion-Positive Non-Small-Cell Lung Cancer.
Not available
S-EPMC11702311 | biostudies-literature
UnknownAge-Related Changes in the Clinical Picture of Long COVID.
Not available
S-EPMC12862131 | biostudies-literature
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