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MetabolomicsGut Commensal Bacteria-Derived Methionine is Required for Host Reproduction by Modulating RNA m6A Methylation of the Insulin Receptor_targeted metabolites

Gut commensal bacteria promote host reproduction by modulating metabolism and nutrition, but the molecular mechanisms by which microbes regulate reproduction remain unclear. Here, we show that gut commensal bacteria promote host reproduction by providing amino-acid methionine, which controls the ...

2025-06-22 | MTBLS12470 | MetaboLights
UnknownCardiac electrophysiological substrate underlying the ECG phenotype and electrogram abnormalities in Brugada syndrome patients.
Not available
S-EPMC4452400 | biostudies-literature
UnknownAcute and two-week effects of neotame, stevia rebaudioside M and sucrose-sweetened biscuits on postprandial appetite and endocrine response in adults with overweight/obesity-a randomised crossover trial from the SWEET consortium.
Not available
S-EPMC11026940 | biostudies-literature
TranscriptomicsHypoxia-induced modulation of gene expression in human adipocytes - A microarray study
Obesity is characterised by expansion of white adipose tissue, accompanied by an inflamatory response. It has been proposed that the inflammatory state observed may be linked to relative hypoxia in clusters of adipocytes distant from vasculature. Adipose tissue hypoxia has been observed in both an...
ORGANISM(S): Homo sapiens 
2012-03-09 | E-GEOD-34007 | biostudies-arrayexpress
UnknownmTORC1 stimulates cell growth through SAM synthesis and m6A mRNA-dependent control of protein synthesis.
Not available
S-EPMC8141029 | biostudies-literature
TranscriptomicsMicroarray Analysis of Genes Regulated by Macrophage-Conditioned Media Treatment of Human Pre-Adipocytes
A major development in the study of obesity is the recognition that the condition is characterised by chronic mild inflammation. Within adipose tissue, this involves the infiltration of macrophages, as well as the direct inflammatory response of the adipocytes and pre-adipocytes. This study has us...
ORGANISM(S): Homo sapiens 
2011-12-21 | E-GEOD-27503 | biostudies-arrayexpress
UnknownTaste manipulation during a food cue-reactivity task: Effects on cue-elicited food craving and subsequent food intake among individuals with overweight and obesity.
Not available
S-EPMC6535365 | biostudies-literature
UnknownRisk factors for the presence of chikungunya and dengue vectors (Aedes aegypti and Aedes albopictus), their altitudinal distribution and climatic determinants of their abundance in central Nepal.
Not available
S-EPMC4361564 | biostudies-literature
UnknownCharacterization of the yeast DGK1-encoded CTP-dependent diacylglycerol kinase.
Not available
S-EPMC2459283 | biostudies-literature
UnknownChange in psychosocial target processes during prenatal depression intervention: A randomized clinical trial.
Not available
S-EPMC12682150 | biostudies-literature
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