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TranscriptomicsPrim_Fibs
To determine changes in gene expression in primary fibroblasts undergoing replicative senescence, a direct comparison between early passage proliferating cells and senescent cells was performed. Frozen stocks of the primary fibroblasts (HMF3) from which the lines HMF3A and HMF3Dwt were derived (O'Ha...
ORGANISM(S): Homo sapiens 
2010-06-09 | E-GEOD-687 | biostudies-arrayexpress
UnknownA transwell assay that excludes exosomes for assessment of tunneling nanotube-mediated intercellular communication.
Not available
S-EPMC5683209 | biostudies-literature
UnknownTowards designer polyolefins: highly tuneable olefin copolymerisation using a single permethylindenyl post-metallocene catalyst.
Not available
S-EPMC10731910 | biostudies-literature
TranscriptomicsHMF3A_with_3Dwt
HMF3A cells, created from adult human mammary fibroblasts by immortalisation with a thermolabile SV40 large T antigen and the catalytic sub-unit of human telomerase, undergo co-ordinated induction of cellular senescence upon inactivation of T antigen. HMF3A cells cease proliferating by 4 days at 39Â...
ORGANISM(S): Homo sapiens 
2010-06-09 | E-GEOD-688 | biostudies-arrayexpress
TranscriptomicsHMF3A_RNAi
HMF3A cells, created from adult human mammary fibroblasts by immortalisation with a thermolabile SV40 large T antigen and the catalytic sub-unit of human telomerase, undergo co-ordinated induction of cellular senescence upon inactivation of T antigen. The pSUPER-retro vector system (Brummelkamp, 200...
ORGANISM(S): Homo sapiens 
2010-06-09 | E-GEOD-690 | biostudies-arrayexpress
UnknownFetal interventions for congenital renal anomalies.
Not available
S-EPMC8192995 | biostudies-literature
UnknownDevelopment and pilot evaluation of an Internet-facilitated cognitive-behavioral intervention for maternal depression.
Not available
S-EPMC3435487 | biostudies-literature
TranscriptomicsWnt/Ca2+/NFAT signaling maintains survival of Ph+ leukemia cells upon inhibition of Bcr-Abl
Although Bcr-Abl kinase inhibitors have proven effective in the treatment of chronic myeloid leukemia (CML), they generally fail to completely eradicate Bcr-Abl+ leukemia cells. To identify genes whose inhibition sensitizes Bcr-Abl+ leukemias to killing by Bcr-Abl inhibitors, we performed an RNAi-ba...
ORGANISM(S): Homo sapiens 
2010-07-15 | E-GEOD-21499 | biostudies-arrayexpress
UnknownBmal1 is involved in the regulation of macrophage cholesterol homeostasis.
Not available
S-EPMC12643489 | biostudies-literature
UnknownA Virulence Associated Siderophore Importer Reduces Antimicrobial Susceptibility of Klebsiella pneumoniae.
Not available
S-EPMC7876324 | biostudies-literature
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