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GenomicsIntegrated approaches reveal determinants of genome-wide binding and function of the transcription factor Pho4
Binding of transcription factors to DNA is a key regulatory step in the control of gene expression. DNA sequences with high affinity for transcription factors occur more frequently in the genome than instances of genes bound or regulated by these factors. Although several mechanisms have been iden...
ORGANISM(S): Saccharomyces cerevisiae 
2011-09-27 | E-GEOD-29506 | biostudies-arrayexpress
GenomicsHog1 controls global reallocation of RNA Pol II upon osmotic shock
When challenged with osmotic shock, S. cerevisiae induces hundreds of genes, despite a global reduction in transcriptional capacity. The mechanisms that regulate this rapid reallocation of transcriptional resources are not known. Here we show that redistribution of RNA Pol II upon stress requires ...
ORGANISM(S): Saccharomyces cerevisiae 
2012-07-15 | E-GEOD-38208 | biostudies-arrayexpress
TranscriptomicsA high resolution map of a cyanobacterial transcriptome
Previous molecular and mechanistic studies have identified several principles of prokaryotic transcription, but less is known about the global transcriptional architecture of bacterial genomes. Here we perform a comprehensive study of a cyanobacterial transcriptome, that of Synechococcus elongatus P...
ORGANISM(S): Synechococcus elongatus PCC 7942 
2011-05-16 | E-GEOD-29264 | biostudies-arrayexpress
TranscriptomicsStructure and Function of a Transcriptional Network Activated by Hog1
Cells regulate gene expression using a complex network of signaling pathways, transcription factors and promoters. To gain insight into the structure and function of these networks we analyzed gene expression in single and multiple mutant strains to build a quantitative model of the Hog1 MAPK-depen...
ORGANISM(S): Saccharomyces cerevisiae 
2008-07-29 | E-GEOD-12270 | biostudies-arrayexpress
TranscriptomicsGenome-Wide Characterization of the Phosphate Starvation Response in Schizosaccharomyces pombe [gene expression data]
Inorganic phosphate is an essential nutrient required by organisms for growth. During phosphate starvation, Saccharomyces cerevisiae activates the phosphate signal transduction (PHO) pathway leading to the expression of the secreted acid phosphatase, PHO5. The fission yeast, Schizosaccharomyces pomb...
ORGANISM(S): Schizosaccharomyces pombe 972h- 
2013-01-02 | E-GEOD-39478 | biostudies-arrayexpress
TranscriptomicsGenome-Wide Characterization of the Phosphate Starvation Response in Schizosaccharomyces pombe
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Schizosaccharomyces pombe 972h- 
2013-01-02 | E-GEOD-39499 | biostudies-arrayexpress
ProteomicsS.cerevisiae - Whole organism, Immunodetection of tagged proteins, normalized data (Ghaemmaghami,nature,2003)
abundance based on normalized data, immunodetection of tagged proteins, Interaction consistency score: 6.5, Coverage: 58
ORGANISM(S): 4932 
2003-00-00 | 420765789 | PAXDB
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