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O-antigen variation of Salmonella Paratyphi A
Typical enteropathogenic Escherichia coli (EPEC) O55:H7 is regarded as the closest relative of enterohemorrhagic E. coli (EHEC) O157:H7. Both serotypes usually express the γ1 intimin subclass and trigger actin polymerazation by the Tir-TccP pathway. However, atypical O55:H7 strains capable of trigg...
ORGANISM(S): Escherichia coli 
Lipopolysaccharide O-antigen is an immunodominant target of protective antibodies. Variation in O-antigen structures limits antibody-mediated cross-protection between closely-related pathogens including Salmonella Typhimurium (STm) and S. Enteritidis (SEn). Bacterial outer membrane vesicles (OMV) ar...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium str. 14028s Wu 
2025-02-21 | PXD056628 | Pride
In a respiratory-infection-model with the avian influenza A H9N2 virus, lung and splenic immune reactions in chickens were studied using a 5K chicken immuno-microarray. Groups of chickens were either mock-immunized (referred to as non-immune), vaccinated with inactivated viral antigen only (immune) ...
ORGANISM(S): Gallus gallus 
O-antigen Loss Modulates Meropenem Resistance in Klebsiella pneumoniae Through Metabolic and Redox Reprogramming
Conditional role of O-specific antigen expression in Pseudomonas aeruginosapathogenicity
Salmonella generates a helper subpopulation lacking the O-antigen polymerase Wzy to improve host cells colonization
Proteins modified with O-GlcNAc and O-GalNAc (the Tn antigen) play critically important roles in many physiological and pathological processes. Comprehensive and site-specific analysis of proteins modified with O-GlcNAc and the Tn antigen advances our understanding of glycoprotein functions and cell...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
Carbapenems are last-line β-lactam antibiotics for multidrug-resistant Gram-negative infections, yet the adaptive routes by which Enterobacterales survive carbapenem stress remain incompletely understood. Here we show that prolonged subinhibitory meropenem exposure promotes O-antigen loss in Klebsie...
ORGANISM(S): Klebsiella pneumoniae 
2025-09-16 | GSE307523 | GEO
Loss of O-Antigen Due to wbbL Mutations is Common and Associated with Increased Mortality in Escherichia coli Bloodstream Infections
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