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TranscriptomicsTranscription profiling of human TLR2/1 stimulated human monocytes with the Mycobacterium tuberculosis derived 19kDa lipopeptide reveals Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response
In innate immune responses, activation of Toll-like receptors (TLRs) triggers direct antimicrobial activity against intracellular bacteria, which in murine, but not human, monocytes and macrophages is mediated principally by nitric oxide. We report here that TLR activation of human macrophages up-re...
ORGANISM(S): Homo sapiens 
2008-06-17 | E-GEOD-8921 | biostudies-arrayexpress
UnknownDivergence of macrophage phagocytic and antimicrobial programs in leprosy.
Not available
S-EPMC2764558 | biostudies-literature
UnknownThe functional landscape of the human phosphoproteome.
Not available
S-EPMC7100915 | biostudies-literature
UnknownA pilot 1-year follow-up randomised controlled trial comparing metacognitive training to psychoeducation in schizophrenia: effects on insight.
Not available
S-EPMC9886217 | biostudies-literature
UnknownCan metacognitive interventions improve insight in schizophrenia spectrum disorders? A systematic review and meta-analysis.
Not available
S-EPMC7610184 | biostudies-literature
UnknownAmphiphysin II (SH3P9; BIN1), a member of the amphiphysin/Rvs family, is concentrated in the cortical cytomatrix of axon initial segments and nodes of ranvier in brain and around T tubules in skeletal muscle.
Not available
S-EPMC2132527 | biostudies-literature
UnknownToolkit and distance coaching strategies: a mixed methods evaluation of a trial to implement care coordination quality improvement projects in primary care.
Not available
S-EPMC8364700 | biostudies-literature
UnknownDevelopment and validation of a risk score for chronic kidney disease in HIV infection using prospective cohort data from the D:A:D study.
Not available
S-EPMC4380415 | biostudies-literature
UnknownIdentification of GSK3186899/DDD853651 as a Preclinical Development Candidate for the Treatment of Visceral Leishmaniasis.
Not available
S-EPMC6407917 | biostudies-literature
ProteomicsOncogenic PKA signaling stabilizes MYC oncoproteins via an aurora kinase A-dependent mechanism
Genetic alterations that activate protein kinase A (PKA) signaling are found across many tumor types, but their downstream oncogenic mechanisms are poorly understood. We used global phosphoproteomics and kinome activity profiling to map the conserved signaling outputs driven by diverse genetic chang...
ORGANISM(S): Homo sapiens (Human) 
2023-02-09 | PXD025508 | Pride
Aurka Fibrolamellar carcinoma Pim2 Pka Myc Liver cancer 
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