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TranscriptomicsCharacterisation of an oesophageal adenocarcinoma cell line (The MFD-1)
A cell line (MFD-1) was derived from a 55-year old male with oesophageal adenocarcinoma. Using different sources of genetic material from normal and tumour tissue surgically resected, peripheral blood and the derived cell line a high concordance of genotypes calls across the whole genome confirms MF...
ORGANISM(S): Homo sapiens 
2016-10-03 | E-MTAB-4590 | biostudies-arrayexpress
GenomicsAuthentication and characterisation of a new oesophageal adenocarcinoma cell line: MFD-1
Whole genome sequencing (WGS) from snap-frozen oesophageal tumour tissue and germline nucleic acids isolated from peripheral blood mononuclear cells (PBMC) was performed as part of the International Cancer Genome Consortium project and OCCAMS consortium (1,2). Filtered read sequences were mapped to ...
ORGANISM(S): Homo sapiens 
2016-09-09 | E-MTAB-4600 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human oesophageal cells stimulated with a low pH environment
Differential gene expression analysis of oesophageal cells stimulated with a low pH environment. Study designed to identify pathways involved in progression of gastro-oesophageal reflux disease through Barrett's oesophagus to adenocarcinoma. Identified many subsets of genes with involvement in patho...
ORGANISM(S): Homo sapiens 
2007-08-25 | E-GEOD-2144 | biostudies-arrayexpress
ProteomicsERBB2 signalling and functions in oesophageal cancer
Oesophageal adenocarcinoma (OAC) is a deadly disease with poor survival statistics and few targeted therapies available. One of the most common molecular aberrations in OAC is amplification or activation of the receptor tyrosine kinase ERBB2, and ERBB2 is targeted in the clinic for this subset of pa...
ORGANISM(S): Homo sapiens (Human) 
2023-01-03 | PXD029180 | Pride
Errb oesophageal cancer phosphoproteomics 
TranscriptomicsATAC-seq of oesophageal adenocarcinoma patient samples
Open chromatin profiling (ATAC-seq) of human oesophageal adenocarcinoma patient samples.
ORGANISM(S): Homo sapiens 
2020-09-30 | E-MTAB-8447 | biostudies-arrayexpress
GenomicsATAC-seq of Oesophageal Cell Lines
ATAC-seq in oesophageal cell lines, OE33 (OAC), FLO1 (OAC), HET1A (Normal)
ORGANISM(S): Homo sapiens 
2016-09-12 | E-MTAB-4209 | biostudies-arrayexpress
UnknownTranslating evidence in a priority setting partnership: knowledge gaps between healthcare providers and oesophageal cancer patients.
Not available
S-EPMC9860237 | biostudies-literature
ProteomicsIdentification of plasma proteins associated with oesophageal cancer chemotherapeutic treatment outcomes using SWATH-MS
Oesophageal adenocarcinoma (OAC) is an aggressive cancer with a five-year survival of <15%, and the incidence is predicted to double within the next 20 years. Current neo-adjuvant chemotherapy treatment strategies only benefit a minority (20-30%) of patients and there are currently no methods availa...
ORGANISM(S): Homo sapiens (Human) 
2022-08-22 | PXD032137 | Pride
Magic regimen Oesophageal cancer Data-independent acquisition Quantitative proteomics Chemotherapy 
TranscriptomicsGene expression profiling of 60 pre-chemotherapy FFPE endoscopic oesophageal adenocarcinoma biopsies
Oesophageal cancer is the ninth most common cancer in the UK and accounts for 5% of all cancer deaths. The incidence of the disease in men has risen 50% in the last 25 years with the commonest pathological subtype in the West being adenocarcinoma, while in East Asia oesophageal squamous cell carcin...
ORGANISM(S): Homo sapiens 
2018-05-10 | E-MTAB-4666 | biostudies-arrayexpress
UnknownOesophageal cancer.
Not available
S-EPMC6168059 | biostudies-literature
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