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TranscriptomicsDifferentially regulated genes in control and c-myc N-myc deficient LT-HSCs
Analysis of HSCs from control and c-myc N-myc deficient long-term hematopoietic stem cells. HSCs lacking both c-myc and N-myc display increased apoptosis rates. Data provide insight into the molecular changes occuring upon complete loss of Myc activity, clarifying the resulting apoptotic mechanism a...
ORGANISM(S): Mus musculus 
2009-02-20 | E-GEOD-12467 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of fission yeast treated with hydrogen peroxide in fission yeast wild type and csx1 mutant cells
Time course experiments of hydrogen peroxide treated cells for both S. pombe wild type and csx1 mutant cells.
ORGANISM(S): Schizosaccharomyces pombe 
2004-10-01 | E-MEXP-176 | biostudies-arrayexpress
TranscriptomicsCOUP-TFII Controls Mouse Postnatal Pancreatic β-Cell Mass through GLP-1 β-Catenin
Pancreatic β-cells have the key homeostatic function of releasing insulin to keep blood glucose in the normal range. It is not fully understood how β-cell mass is determined. Ablation of a nuclear receptor, chicken ovalbumin upstream promoter transcription factor II (COUP-TFII), in mouse pancreat...
ORGANISM(S): Rattus norvegicus 
2011-10-06 | E-GEOD-30526 | biostudies-arrayexpress
UnknownArtificial intelligence and radiologists in prostate cancer detection on MRI (PI-CAI): an international, paired, non-inferiority, confirmatory study.
Not available
S-EPMC11587881 | biostudies-literature
TranscriptomicsComparative genomic hybridization of Clostridium sporogenes and Clostridium botulinum strains
Clostridium botulinum is a heterogeneous Gram-positive species that comprises four genetically and physiologically distinct groups of bacteria that share the ability to produce botulinum neurotoxin, the most poisonous toxin known to man, and the causative agent of botulism, a severe disease of human...
ORGANISM(S): Clostridium botulinum 
2007-05-23 | E-TABM-264 | biostudies-arrayexpress
TranscriptomicsCP001: Modulation of glutamine metabolism by the PI3K-PKB/c-akt-FOXO network regulates autophagy
The PI3K-PKB/c-akt-FOXO signalling network provides a major intracellular hub for regulation of cell proliferation, survival and stress resistance1. Here we report a novel function for FOXO transcription factors in regulating autophagy through modulation of intracellular glutamine levels. To identif...
ORGANISM(S): Mus musculus 
2012-07-21 | E-GEOD-35701 | biostudies-arrayexpress
TranscriptomicsEffect of acute ethanol on medidal prefronal cortex across BXD genetic mapping panel and progenitors.
In order to elucidate the molecular mechanisms underlying individual variation in sensitivity to ethanol we profiled the prefrontal cortex transcriptomes of two inbred strains that exhibit divergent responses to acute ethanol, the C57BL6/J (B6) and DBA/2J (D2) strains, as well as 27 members of the B...
ORGANISM(S): Mus musculus 
2011-12-01 | E-GEOD-28515 | biostudies-arrayexpress
TranscriptomicsArray results for differential gene expression in 661W, a mouse cone photoreceptor-derived cell line, comparing cells incubated with vehicle controls vs. those treated with either of two 7-dehdyrocholesterol-derived oxysterols or cholesterol
RELEVANCE: Smith-Lemli-Opitz syndrome (SLOS) is a human disease caused by mutations in the gene coding for the enzyme DHCR7 (7-dehydrocholesterol (7DHC) reductase), which catalyzes the final step of cholesterol biosynthesis. Accumulated 7DHC in tissues and body fluids of SLOS patients gives rise t...
ORGANISM(S): Mus musculus 
2021-03-20 | E-MTAB-10055 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of matching human primary head and neck squamous cell carcinomas and cervical lymph node metastases.
An experiment was performed to investigate the perservation of gene expression upon metastasis of primary head and neck squamous cell carcinomas to the cervical lymph node.
ORGANISM(S): Homo sapiens 
2006-10-23 | E-TABM-114 | biostudies-arrayexpress
TranscriptomicsCP003: Modulation of glutamine metabolism by the PI3K-PKB/c-akt-FOXO network regulates autophagy
The PI3K-PKB/c-akt-FOXO signalling network provides a major intracellular hub for regulation of cell proliferation, survival and stress resistance1. Here we report a novel function for FOXO transcription factors in regulating autophagy through modulation of intracellular glutamine levels. To identif...
ORGANISM(S): Mus musculus 
2012-07-21 | E-GEOD-35703 | biostudies-arrayexpress
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