Sort   by:  
 Page size 
TranscriptomicsEarly life adversity alters normal sex-dependent developmental dynamics of DNA methylation in rhesus monkeys
This study mapped the genome wide DNA methylation changes in CD3+ T lymphocytes from rhesus monkeys from postnatal day 14 through two years of age in both males and females and determined the impact of maternal deprivation on the DNA methylation profile. We show here that DNA methylation profiles ev...
ORGANISM(S): Macaca mulatta 
2016-07-06 | E-GEOD-84024 | biostudies-arrayexpress
UnknownPolycythemia Vera: An Appraisal of the Biology and Management 10 Years After the Discovery of JAK2 V617F.
Not available
S-EPMC4979103 | biostudies-literature
UnknownETV6-NCOA2 fusion induces T/myeloid mixed-phenotype leukemia through transformation of nonthymic hematopoietic progenitor cells.
Not available
S-EPMC9906988 | biostudies-literature
UnknownImproved Survival for Children and Young Adults With T-Lineage Acute Lymphoblastic Leukemia: Results From the Children's Oncology Group AALL0434 Methotrexate Randomization.
Not available
S-EPMC6366301 | biostudies-literature
TranscriptomicsTranscription profiling of wild type and mutant fission yeast exposed to different intensities of H202 and two other oxidants
We studied transcriptional responses of the fission yeast Schizosaccharomyces pombe to different intensities of H2O2 stress as well as two other oxidants: menadione sodium bisulfite and tert-butyl hydroperoxide. DNA microarrays were used to study the changes in expression profiles and the transcrip...
ORGANISM(S): Schizosaccharomyces pombe 
2007-12-07 | E-MEXP-1083 | biostudies-arrayexpress
TranscriptomicsPopulation genetic structure of the Ashkenazi Jewish population
The Ashkenazi Jewish population has long been considered a genetic isolate and presumed to have the genetic signatures of founder effects and isolation. We genotyped a large cohort of Ashkenazi Jews and analyzed their genetic structure compared to other worldwide populations. We genotyped 471 normal...
ORGANISM(S): Homo sapiens 
2010-08-16 | E-GEOD-23636 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of lung carcinoma and brain glioblastoma cells were analalyzed, with microarrays run both for control and treatment with dichloroacetate reveals a mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis inhibits cancer growth
The unique metabolic profile of most cancers (aerobic glycolysis) might confer apoptosis-resistance and be therapeutically targeted. Compared to normal cells, several human cancers have high mitochondrial membrane potential and low expression of the K+ channel Kv1.5, both contributing to apoptosis-r...
ORGANISM(S): Homo sapiens 
2008-06-14 | E-GEOD-6014 | biostudies-arrayexpress
GenomicGenome-wide Association Study of Adiposity in Samoans

The research goal of this study is to identify genetic variation that increases susceptibility to obesity and cardiometabolic phenotypes among adult Samoans using genome-wide association (GWAS) methods. DNA from peripheral blood and phenotypic information were collected from 3,119 adult Samoans, ...

phs000914 | dbGaP
TranscriptomicsTranscriptional Control by the FATC Domain of Saccharomyces cerevisiae Tra1
Tra1 is a component of the Saccharomyces cerevisiae SAGA and NuA4 complexes and a member of the phosphatidylinositol 3-kinase (PI3K) related kinase family that contain a C- terminal PI3K domain followed by a ~ 35-residue FATC domain. We have characterized four alleles with single residue changes in ...
ORGANISM(S): Saccharomyces cerevisiae 
2013-01-30 | E-GEOD-13561 | biostudies-arrayexpress
UnknownOutcome Measures in Rheumatology - Interventions for medication Adherence (OMERACT-Adherence) Core Domain Set for Trials of Interventions for Medication Adherence in Rheumatology: 5 Phase Study Protocol.
Not available
S-EPMC5870260 | biostudies-literature
Sort   by:  
 Page size