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TranscriptomicsWhole genome gene expression profiling in CD4+ T-cells, FACS-sorted based on CADM1/CD7 expression levels, in Adult T-cell Leukemia-lymphoma (ATL) patients, HTLV-1 carriers, and in healthy volunteers.
CADM1 overexpresion and stepwise downregulation of CD7 in CD4+T-cells from ATL patients and HTLV-1 carriers accurately reflect the process of disease, i.e., oligoclonally and clonally exanding cells are accumulated in D (CADM1posCD7dim) and N (CADM1posCD7neg) populations, respectively. Moreover, gen...
ORGANISM(S): Homo sapiens 
2014-06-02 | E-GEOD-55851 | biostudies-arrayexpress
TranscriptomicsExpression data from CD4+ NaM-CM-/ve T cells under Treg-inducing condition in the presence or absence of butyrate
Commensal bacteria shapes gut immune system. Colonization bacteria increase the frequency of regulatory T cells, however, the molecular mechanisms has not yet been unknown. To reveal the mechanism, we isolated NaM-CM-/ve CD4+ T cells from spleen of C57BL/6 mice and cultured the cells under Treg-indu...
ORGANISM(S): Mus musculus 
2013-11-20 | E-GEOD-49619 | biostudies-arrayexpress
GenomicsCommensal microbe-derived butyrate epigenetically induces colonic regulatory T cells
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2013-11-20 | E-GEOD-49655 | biostudies-arrayexpress
GenomicsGenome-wide measurement of acetylated histone H3 in naïve cells under Treg-inducing conditon
To investigate the molecular mechanism how butyrate promoter differentiation of naïve T cells into regulatory T cells Examination of acetylated histone H3 during the differentiation of regulatory T cells in the presence or absence of butyrate
ORGANISM(S): Mus musculus 
2013-11-20 | E-GEOD-49653 | biostudies-arrayexpress
UnknownA case with hepatic immune-related adverse events caused by nivolumab exhibiting impaired accumulation of regulatory T cells.
Not available
S-EPMC8298218 | biostudies-literature
TranscriptomicsGene expression of the colonic epithelial cells in CRB mice fed with HFD and LFD
To elucidate the mechamisms of colonic Treg cell induction by microbial metabolite(s), chroloform-resistant bacteria (CRB)-associated mice was developed and given low-fiber diet (LFD) and high-fiber diet (HFD). The colonic epithelial cells were isolated and gene expression profiles were analyzed by ...
ORGANISM(S): Mus musculus 
2014-08-11 | E-GEOD-41104 | biostudies-arrayexpress
UnknownCD8+ T Cells Mediate Female-Dominant IL-4 Production and Airway Inflammation in Allergic Asthma.
Not available
S-EPMC4619475 | biostudies-literature
UnknownDistinct Roles for CXCR6(+) and CXCR6(-) CD4(+) T Cells in the Pathogenesis of Chronic Colitis.
Not available
S-EPMC3686755 | biostudies-literature
UnknownEssential functions of Runx/Cbfβ in gut conventional dendritic cells for priming Rorγt+ T cells.
Not available
S-EPMC6907387 | biostudies-literature
UnknownAdvanced human T-cell leukemia virus type 1 carriers and early-stage indolent adult T-cell leukemia-lymphoma are indistinguishable based on CADM1 positivity in flow cytometry.
Not available
S-EPMC4452161 | biostudies-literature
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