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MetabolomicsSeed Metabolome Analysis of a Transgenic Rice Line Expressing Cholera Toxin B-subunit
Rice (Oryza sativa L.) is a candidate crop for production of plant-based vaccines by genetic engineering technologies. MucoRice-CTB has been developed as a rice-seed-based vaccine against cholera by transgenic expression of modified cholera toxin B-subunit (CTB) under the RNA interference (RNAi)-med...
2017-08-30 | MTBLS437 | MetaboLights
TranscriptomicsOffspring from oocytes derived from in vitro primordial germ cell-like cells in mice
Reconstitution of female germ-cell development in vitro is a key challenge in reproductive biology and medicine. We show here that female (XX) embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) in mice are induced into primordial germ cell-like cells (PGCLCs), which, when aggrega...
ORGANISM(S): Mus musculus 
2012-11-05 | E-GEOD-40716 | biostudies-arrayexpress
TranscriptomicsInduction of the mouse germ cell fate by transcription factors in vitro [exp2]
The germ cell lineage ensures the continuity of life through the generation of male and female gametes, which unite to form a totipotent zygote. We have established a culture system that recapitulates the mouse germ-cell specification pathway: Using cytokines, embryonic stem cells (ESCs)/induced plu...
ORGANISM(S): Mus musculus 
2013-08-04 | E-GEOD-46854 | biostudies-arrayexpress
TranscriptomicsInduction of the mouse germ cell fate by transcription factors in vitro [exp1]
The germ cell lineage ensures the continuity of life through the generation of male and female gametes, which unite to form a totipotent zygote. We have established a culture system that recapitulates the mouse germ-cell specification pathway: Using cytokines, embryonic stem cells (ESCs)/induced plu...
ORGANISM(S): Mus musculus 
2013-08-04 | E-GEOD-43775 | biostudies-arrayexpress
MetabolomicsWax ester and lipophilic compound profiling of Euglena gracilis by gas chromatography-mass spectrometry: toward understanding of wax ester fermentation under hypoxia
Lipids are being increasingly used as biodiesel feedstock, and several saturated wax esters from Euglena gracilis are candidates for outdoor bulk production. Wax ester fermentation in Euglena is strongly increased by hypoxia, but key events underlying the metabolic shift toward wax ester biosynthesi...
2014-09-04 | MTBLS113 | MetaboLights
TranscriptomicsPRDM14 Ensures a Naïve Pluripotency by a Dual Mechanism Involving Signaling and Epigenetic Pathways in Mouse Embryonic Stem Cells
Mouse embryonic stem cells (mESCs) fluctuate between a naïve inner cell mass (ICM)-like state and a primed epiblast-like state of pluripotency in serum, but are harnessed exclusively in a distinctive, apparently more naïve state of pluripotency (the ground state) with inhibitors for mitogen-activate...
ORGANISM(S): Mus musculus 
2013-01-18 | E-GEOD-42580 | biostudies-arrayexpress
GenomicsPRDM14 Ensures Naïve Pluripotency through Dual Regulation of Signaling and Epigenetic Pathways in Mouse Embryonic Stem Cells
Mouse embryonic stem cells (mESCs) fluctuate between a naïve inner cell mass (ICM)-like state and a primed epiblast-like state of pluripotency in serum, but are harnessed exclusively in a distinctive, naïve state of pluripotency that more faithfully captures the ICM state (the ground state) with i...
ORGANISM(S): Mus musculus 
2013-01-18 | E-GEOD-42616 | biostudies-arrayexpress
UnknownTDRD5 is required for retrotransposon silencing, chromatoid body assembly, and spermiogenesis in mice
Not available
S-JCBD-201009043 | bioimages
ProteomicsProteomic analysis of cochlear perilymph in a mouse model of Alzheimer's disease
This study referred to the changes in protein abundance of App(NL-GF/NL-GF) and App(wt/wt) mice perilymph. Liquid chromatography-tandem mass spectrometry with MS2-based quantification of tandem mass tag was utilized.
ORGANISM(S): Mus Musculus (mouse) 
2024-04-15 | PXD046317 | JPOST Repository
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