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TranscriptomicsTranscription profiling of human NK-cell associated receptors expression in EBV-positive gamma-delta T cell lines.
The contribution of chronic antigen stimulation to the occurrence of lymphoproliferative disorder (LPD) with the gamma-delta T-cell lineage is unclear, despite the fact that Epstein-Barr virus (EBV) positive T-cell LPD is derived from antigen-stimulated cytotoxic T-cells. Given the possible associat...
ORGANISM(S): Homo sapiens 
2009-12-18 | E-GEOD-13906 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of four human Adult T-cell leukemia (ATL) cell lines treated with proteasome inhibitor, bortezomib
Adult T-cell leukemia (ATL) is a fatal neoplasia derived from HTLV-1 infected T lymphocytes exhibiting constitutive activation of NF-kB. To elucidate the complex molecular mechanism of anti-tumor effect of the proteasome inhibitor, bortezomib in ATL cells, we attempted to perform gene expression pr...
ORGANISM(S): Homo sapiens 
2008-06-14 | E-GEOD-6034 | biostudies-arrayexpress
TranscriptomicsDown-regulation of miR-92 in human plasma is a novel marker for acute leukemia patients
MicroRNAs are a family of 19- to 25-nucleotides noncoding small RNAs that primarily function as gene regulators. Aberrant microRNA expression has been described for several human malignancies, and this new class of small regulatory RNAs has both oncogenic and tumor suppressor functions. Despite th...
ORGANISM(S): Homo sapiens 
2010-05-16 | E-GEOD-14772 | biostudies-arrayexpress
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