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MetabolomicsAntidiabetic and cardiovascular beneficial effects of a liver-localized mitochondrial uncoupler
Inducing mitochondrial uncoupling (mUncoupling) is an attractive therapeutic strategy for treating metabolic diseases because it leads to calorie-wasting by reducing the efficiency of oxidative phosphorylation (OXPHOS) in mitochondria. Here we report a safe mUncoupler, OPC-163493, which has unique p...
2019-05-24 | MTBLS836 | MetaboLights
UnknownThe mitochondrial genome analysis of a stonefly, Nemoura longicercia Okamoto, 1922 (Plecoptera: Nemouridae).
Not available
S-EPMC9621250 | biostudies-literature
UnknownThe first complete mitochondrial genome of Euroleon coreanus (Okamoto, 1926) (Neuroptera: Myrmeleontidae) and its phylogeny.
Not available
S-EPMC8205084 | biostudies-literature
TranscriptomicsA developmental coordinate of the spectrum of pluripotency among mice, monkeys, and humans
The epiblast (EPI) is the origin of all somatic and germ cells in mammals, and of the spectrum of pluripotent stem cells (PSCs) in vitro. To explore the ontogeny of human/primate pluripotency, we performed comprehensive single-cell RNA sequencing for pre- and post-implantation EPI development in cyn...
ORGANISM(S): Mus musculus 
2016-08-24 | E-GEOD-74767 | biostudies-arrayexpress
UnknownTranscriptomics Provide Insights into the Photoperiodic Regulation of Reproductive Diapause in the Green Lacewing, Chrysoperla nipponensis (Okamoto) (Neuroptera: Chrysopidae).
Not available
S-EPMC10889211 | biostudies-literature
ProteomicsProteome driven re-evaluation and functional annotation of Streptococcus pyogenes SF370 genome.
Shotgun proteomic analysis for re-evaluation of genome S. pyogenes SF370, by using RP-HPLC ion trap MS/MS with six-frame database.
ORGANISM(S): Streptococcus pyogenes M1 GAS 
2011-11-18 | PRD000562 | Pride
TranscriptomicsA new strategy to identify the long-distance mobile peptides from xylem sap.
Total RNAs were extracted from internodes and roots of 18 day-after-germination soybean plants, and the expression levels of the genes that encode xylem sap associated peptides or proteins were analyzed.
ORGANISM(S): Glycine max 
2015-10-23 | E-MTAB-5052 | biostudies-arrayexpress
TranscriptomicsNuclear receptor, RORa plays a critical role in obesity-associated inflammation, hepatic steatosis, and insulin resistance
We demonstrated that RORa-deficient staggerer mice (RORasg/sg) fed with a high fat diet (HFD) showed reduced adiposity and hepatic triglyceride levels compared to wild type (WT) littermates and were resistant to the development of hepatic steatosis, adipose-associated inflammation, and insulin resis...
ORGANISM(S): Mus musculus 
2011-04-30 | E-GEOD-23736 | biostudies-arrayexpress
UnknownMechanisms Underlying Spontaneous Action Potential Generation Induced by Catecholamine in Pulmonary Vein Cardiomyocytes: A Simulation Study.
Not available
S-EPMC6628582 | biostudies-literature
UnknownCysteinylprolyl imide (CPI) peptide: a highly reactive and easily accessible crypto-thioester for chemical protein synthesis.
Not available
S-EPMC6566460 | biostudies-literature
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