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Genomicsena-DATASET-UT-Ped-15-12-2014-06:44:14:477-357 - samples
Whole-exome sequencing in 16 RMS cases Whole-transcriptome sequencing in 8 RMS cases
EGAD00001001105 | EGA
GenomicsIntegrated genetic and epigenetic analysis defines novel molecular clusters in rhabdomyosarcoma
Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in childhood. To unravel the genetic/epigenetic basis of RMS, we studied 60 RMS cases using whole exome/transcriptome sequencing, copy number (CN) profiling, and DNA methylome analysis. Based on DNA methylation patterns, RMS was clustered...
EGAS00001000884 | EGA
GenomicsRMS_Infinium450K
Infinium 450K in Rhabdomyosarcoma
EGAD00010000897 | EGA
GenomicsDepartment of Pediatrics, The University of Tokyo Data Access Committee
Data Access Committee EGAC00001000207
EGAC00001000207 | EGA
TranscriptomicsScreening of new target genes specifically activated by deregulated E2F
To identify genes specifically activated by deregulated E2F, we examined gene expression profiles using human normal fibroblasts (HFFs), which were starved of serum and re-stimulated with serum, over-expressed with E2F1 or expressed with adenovirus E1a to forcedly inactivate RB. To identify genes ac...
ORGANISM(S): Homo sapiens 
2015-11-20 | E-GEOD-67887 | biostudies-arrayexpress
TranscriptomicsScreening of genes activated by phsiological E2F induced by gorwth stimulation
To identify genes activated by physiological E2F, we examined gene expression profiles using human normal fibroblasts (HFFs), which were starved of serum and re-stimulated with serum. To identify genes activated by growth stimulation, human normal fibroblasts (HFFs) were starved of serum for 48 hr, ...
ORGANISM(S): Homo sapiens 
2015-11-20 | E-GEOD-68081 | biostudies-arrayexpress
ProteomicsCoRest’s acetylation acts as a temporal gate for activity-dependent transcription, limiting behavioral flexibility in Drosophila
In this project, to identify the proteins interacting with Rpd3 in the Drosophila mushroom body, the tandem affinity-purification(TAP) was performed. After in-solution digestion, the purified protein complex was analyzed by LC-MS/MS analysis using Orbitrap velos pro. PTM analysis was also performed...
ORGANISM(S): Drosophila Melanogaster (fruit Fly) 
2020-12-07 | PXD021294 | JPOST Repository
TranscriptomicsGene expression profile of L428 cells conditional expressing PU.1
PU.1 is an Ets family transcription factor that is essential for the differentiation of both myeloid and lymphoid cells. PU.1 is down-regulated in classical Hodgkin lymphoma cells via methylation of the PU.1 promoter. To evaluate whether down-regulation of PU.1 is essential for the growth of cHL cel...
ORGANISM(S): Homo sapiens 
2012-11-22 | E-GEOD-42437 | biostudies-arrayexpress
TranscriptomicsGene expression profile of KM-H2 cells conditional expressing PU.1
PU.1 is an Ets family transcription factor that is essential for the differentiation of both myeloid and lymphoid cells. PU.1 is down-regulated in classical Hodgkin lymphoma cells via methylation of the PU.1 promoter. To evaluate whether down-regulation of PU.1 is essential for the growth of cHL cel...
ORGANISM(S): Homo sapiens 
2012-11-22 | E-GEOD-42440 | biostudies-arrayexpress
ProteomicsInteractome analysis for Kdm4B
In this project, to identify the proteins interacting with Rpd3 in the Drosophila mushroom body, the tandem affinity-purification(TAP) was performed. After in-solution digestion, the purified protein complex was analyzed by LC-MS/MS analysis using Orbitrap velos pro. PTM analysis was also performed ...
ORGANISM(S): Drosophila Melanogaster (fruit Fly) 
2023-08-12 | PXD039097 | JPOST Repository
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