Olfactory sensory neurons

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Transcriptomics (202)
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Organisms

Mus musculus (177)
Homo sapiens (14)
Drosophila melanogaster (12)
Danio rerio (11)
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Apis mellifera (3)
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Mus musculus (2)
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Severe acute respiratory syndrome coronavirus 2 (1)
Ooceraea biroi (1)
Caenorhabditis elegans (1)
Xenopus laevis (1)
synthetic construct (1)

Organisms

Mus musculus (118)
Drosophila melanogaster (9)
Danio rerio (7)
Caenorhabditis elegans (3)
Homo sapiens (3)
Apis mellifera (2)
Sus scrofa (2)
Rattus norvegicus (2)
Ooceraea biroi (1)
Protopterus amphibius (1)
Xenopus laevis (1)

Repository

ENA (179)
geo (144)
biostudies-arrayexpress (83)
MassIVE (5)
EGA (2)
pride (2)
BioModels (1)
iProX (1)
jPOST (1)
MetaboLights (1)

Tissue

Brain (1)
Olfactory bulb (1)
Olfactory receptor neuron (1)

Disease

Parkinson's disease (1)
Not applicable (1)
Normal (1)

Technology Type

Mass Spectrometry (2)
Illumina HiSeq 2500 (1)
Mass spectrometry (1)
Bottom-up proteomics (1)
Shotgun proteomics (1)

Instrument Platform

Illumina HiSeq 2500 (7)
Illumina HiSeq 2000 (3)
Illumina NovaSeq 6000 (2)
Q Exactive HF (2)
HiSeq X Ten (1)
Illumina MiSeq (1)
Orbitrap Exploris 480 (1)
Orbitrap Fusion Lumos (1)
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Liquid Chromatography MS - positive - reverse phase (1)
Liquid Chromatography MS - negative - reverse phase (1)

Publication Date

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2013 (9)
2011 (9)
2017 (9)
2007 (8)
2018 (8)
2010 (5)
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2005 (2)
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2006 (2)

Metabolite Name

2-(2,5-dihydroxy-4-methoxyphenyl)-3,5,6,7-tetrahydroxy-3,4-dihydro-2H-1-benzopyran-4-one; 3-(2,5-dihydroxy-4-methoxyphenyl)-1-(2,3,4,6-tetrahydroxyphenyl)propane-1,2-dione; 3,5,7-trihydroxy-6-methoxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one; 3,5,7-trihydroxy-6-methoxy-2-(2,3,4-trihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one; 3,5,7-trihydroxy-6-methoxy-2-(2,4,5-trihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one; (1)
N-acetyl-L-2-aminoadipate(2-); (1)
VI2Fuc-nLc6; (1)
3',5'-Diiodo-L-thyronine 4'-O-sulfate; (1)
TG(22:1(13Z)/19:2n6/22:6(4Z,7Z,10Z,13Z,16Z,19Z)); (1)
TG(15:0/22:2(13Z,16Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)); TG(15:0/22:4(7Z,10Z,13Z,16Z)/22:4(7Z,10Z,13Z,16Z)); TG(15:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/22:2(13Z,16Z)); TG(22:2(13Z,16Z)/15:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)); TG(22:4(7Z,10Z,13Z,16Z)/15:0/22:4(7Z,10Z,13Z,16Z)); (1)
TG(14:0/15:0/24:0); TG(14:0/24:0/15:0); TG(15:0/14:0/24:0); TG(15:0/16:0/22:0); TG(15:0/18:0/20:0); (1)
Shoyuflavone C; (1)
4-Hydroxycinnamoylagmatine; (1)
Tipranavir; (1)
N-Acetyltryptophan; Methylphenobarbital; Nigellicine; cyclic 6-Hydroxymelatonin; (1)
Sialyllacto-N-tetraose a; Sialyllacto-N-neotetraose c; Sialyllacto-N-tetraose b; LS tetrasaccharide d; Sialyllacto-N-tetraose c; (1)
Ganglioside GD3 (d18:1/12:0); (1)
L-Tryptophan; D-Tryptophan; 3-Hydroxymethylantipyrine; Ethotoin; (Â±)-Tryptophan; (1)
Vinylacetylglycine; Trimethadione; 5-ethyl-5-methyl-2,4-oxazolidinedione; 6-Oxopiperidine-2-carboxylic acid; (1)
Glutamyltryptophan; Tryptophyl-Glutamate; gamma-Glutamyltryptophan; (1)
Norlaudanosoline; Pipermethystine; noroxymorphone; (1)
Ethyl 2-mercaptopropionate; Methyl 3-mercaptobutanoate; Methyl 3-(methylthio)propanoate; Ethyl 2-(methylthio)acetate; Ethyl 3-mercaptopropanoic acid; (1)
Olmesartan; (1)
De-O-methylsterigmatocystin; Aurantricholide B; {3-[2-(3,5-dihydroxyphenyl)ethyl]phenyl}oxidanesulfonic acid; Dihydroresveratrol 3-sulfate; Dihydroresveratrol 4'-sulfate; (1)
1-Isothiocyanato-8-(methylthio)octane; (1)
PA(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/24:1(15Z)); PA(24:1(15Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)); (1)
Zizybeoside I; Armillaricin; Benzyl gentiobioside; 15beta-hydroxycyproterone acetate; (1)
6,8-bis[2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-3,4-dihydro-2H-1-benzopyran-4-yl]-2-(3-hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol; 8-[3,7-dihydroxy-2-(3-hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-yl]-2-(3,4-dihydroxyphenyl)-6-[2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-3,4-dihydro-2H-1-benzopyran-4-yl]-3,4-dihydro-2H-1-benzopyran-3,5,7-triol; 6-[3,7-dihydroxy-2-(3-hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-yl]-2-(3,4-dihydroxyphenyl)-8-[2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-3,4-dihydro-2H-1-benzopyran-4-yl]-3,4-dihydro-2H-1-benzopyran-3,5,7-triol; (1)
Simmondsin 2'-ferulate; Astin I; 4-Hydroxytamoxifen-N-glucuronide; 6-{[1-(2-{[3-(3,4-dimethoxyphenyl)-1-hydroxypropylidene]amino}ethyl)-3-methoxy-4-oxocyclohexa-2,5-dien-1-yl]oxy}-3,4,5-trihydroxyoxane-2-carboxylic acid; 6-{[1-(2-{[2-(3,4-dimethoxyphenyl)ethyl]-C-hydroxycarbonimidoyl}ethyl)-3-methoxy-4-oxocyclohexa-2,5-dien-1-yl]oxy}-3,4,5-trihydroxyoxane-2-carboxylic acid; (1)
Indolelactic acid; 5-Methoxyindoleacetate; Cinnamoylglycine; Edulitine; Methyl 1-methoxy-1H-indole-3-carboxylate; (1)
P-Cresol glucuronide; 2-O-Benzoyl-D-glucose; D-Vacciniin; (1)
(Â±)-Ribaline; 5-Amino-6-(4-hydroxy-2-butenoyl)-2,2-dimethyl-4-chromanone; (1)
CD 1790; (1)
Tetraphyllin B; (1)

IsPrivate

False (1)

First Public Date

2025 (25)
2021 (20)
2023 (19)
2014 (19)
2022 (15)
2017 (15)
2024 (13)
2020 (13)
2026 (12)
2018 (8)
2013 (6)
2016 (5)
2015 (5)
2019 (4)

Modelling Approach

Ordinary differential equation model (1)

Study type

Transcription profiling by array (52)
RNA-seq of coding RNA (22)
ChIP-chip by tiling array (2)
RNA-seq of coding RNA from single cells (2)
Methylation profiling by high throughput sequencing (2)
RNA-seq of non coding RNA (2)
Unknown experiment type (1)

Release Date

2025 (101)
2022 (87)
2016 (70)
2021 (69)
2020 (69)
2015 (65)
2023 (65)
2024 (61)
2014 (54)
2018 (53)
2017 (52)
2019 (50)
2013 (42)
2012 (40)
2011 (32)
2010 (27)
2008 (27)
2009 (22)
2007 (14)
2026 (9)
2006 (6)
2005 (6)
2004 (5)
2001 (4)
2000 (4)
1998 (4)
2003 (3)
2002 (3)
1999 (2)
1997 (1)

Lab affiliation

Faculty Scientist,Institute of Bioinformatics, International Technology Park, Bangalore 560066, India (1)
Medizinisches Proteom-Center, Ruhr-Universität Bochum, ZKF 1.055, Universitätsstraße 150, 44801 Bochum, Germany (1)

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Transcription profiling of murine olfactory epithelium during neuronal death and replacement to study adult neurogenesis in the olfactory epithelium

Expression profiling of mRNA abundance in the adult mouse olfactory epithelium during replacement of OSNs forced by the bilateral ablation of the olfactory bulbs. The experiment was done on 6 week old male C57Bl/6 mice. Olfactory epithelium tissue samples were collected on days 1, 5, and 7 after b...

ORGANISM(S): Mus musculus

2007-09-04 | E-GEOD-2437 | biostudies-arrayexpress

Transcription profiling of olfactory epithelia isolated from wild type and KLF7 null mice to identify potential KLF7 target genes in olfactory sensory neurons.

KLF7 null mice show profound axonal growth defects in the olfactory epithelium. The goal of this study was the identification of potential KLF7 target genes in olfactory sensory neurons. Experiment Overall Design: Olfactory epithelia were isolated from 3 wildtype and 3 mutant 1 day old pups and the ...

ORGANISM(S): Mus musculus

2007-12-01 | E-GEOD-3595 | biostudies-arrayexpress

Transcription profiling of mouse olfactory epithelium frpm Harlequin mutants compared to littermate controls

Microarray analysis of gene expression in the olfactory epithelium of Harlequin mouse as a model of oxidative-stress induced neurodegeneration of olfactory sensory neurons Experiment Overall Design: Olfactory epithelium from Harlequin mutant mice and littermate control mice was microdissected for RN...

ORGANISM(S): Mus musculus

2008-06-14 | E-GEOD-6485 | biostudies-arrayexpress

Transcription profiling of mouse olfactory sensory neurons

The overall aim of the experiment is to understand the phenotype of mature mouse olfactory sensory neurons by analyzing the transcripts expressed and enriched in them as compared to the rest of the cell types in the olfactory epithelium (consisting of immature neurons, supporting cells, progenitor c...

ORGANISM(S): Mus musculus

2008-06-13 | E-GEOD-4915 | biostudies-arrayexpress

Single-cell transcriptomics reveals receptor transformations during olfactory neurogenesis

We report RNA sequencing of single olfactory neurons from mouse olfactory epithelium in developmental progression from progenitors to precursors to immature neurons to mature neurons. Most mature neurons expressed only one of ~ 1000 odorant receptor genes (Olfrs) at high levels, whereas many immatur...

ORGANISM(S): Mus musculus

2015-11-25 | E-GEOD-75413 | biostudies-arrayexpress

Comparison of gene expression profiles in olfactory epithelium from Atf5+/+ and Atf5-/- mice

We have found that the expression pattern of Atf5 is highly restricted to the olfactory system, strongly suggesting that Atf5 is an olfactory sensory neuron-specific transcription factor. To test this possiblity, we compared gene expression profiles in olfactory epithelium (septa and turbinates) fro...

ORGANISM(S): Mus musculus

2012-10-30 | E-GEOD-37609 | biostudies-arrayexpress

Effects of H2be loss of function on gene expression in the main olfactory epithelium (MOE) of 6-month old mice.

We have identified a replication-independent histone variant, Hist2h2be (referred to herein as H2be), which is expressed exclusively by olfactory chemosensory neurons. Levels of H2BE are heterogeneous among olfactory neurons, but stereotyped according to the identity of the co-expressed olfactory re...

ORGANISM(S): Mus musculus

2012-09-01 | E-GEOD-39515 | biostudies-arrayexpress

Effects of H2be ectopic over-expression on gene expression in the main olfactory epithelium (MOE) of 5-week old mice.

ORGANISM(S): Mus musculus

2012-09-01 | E-GEOD-39514 | biostudies-arrayexpress

Deep sequencing of the murine olfactory receptor neuron transcriptome

The recent development of next-generation sequencing (NGS) techniques encouraged us to assess the transcriptome of the murine OE. We analyzed RNA from OEs of female and male adult mice and from fluorescence-activated cell sorting (FACS)-sorted olfactory receptor neurons (ORNs) obtained from transgen...

ORGANISM(S): Mus musculus

2015-01-21 | E-GEOD-53793 | biostudies-arrayexpress

single olfactory sensory neurons

PRJEB7425 | ENA

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