Sort   by:  
 Page size 
Unknown#COVIDisAirborne: AI-Enabled Multiscale Computational Microscopy of Delta SARS-CoV-2 in a Respiratory Aerosol.
We seek to completely revise current models of airborne transmission of respiratory viruses by providing never-before-seen atomic-level views of the SARS-CoV-2 virus within a respiratory aerosol. Our work dramatically extends the capabilities of multiscale computational microscopy to address the sig...
S-EPMC8609898 | biostudies-literature
TranscriptomicsToxicogenomic analysis of rural and urban air particles
Atmospheric particulate matter (PM) is a recognized risk factor for the global burden of disease in human populations. We are presenting here the application of toxicogenomics in the evaluation of the toxic effects of organic content of atmospheric particle matter (PM), from urban and rural environm...
ORGANISM(S): Danio rerio 
2015-10-26 | E-GEOD-53522 | biostudies-arrayexpress
TranscriptomicsBlood genomic expression profile for ischemic stroke (IS)
Stroke is a “brain attack” cutting off vital blood, and consequently the nutrients and oxygen vital to the brain cells that control everything we do. Stroke is a complex disease with unclear pathogenesis resulting from environmental and genetic factors. To better understand IS´s etiology, we perform...
ORGANISM(S): Homo sapiens 
2011-12-31 | E-GEOD-22255 | biostudies-arrayexpress
UnknownEstimating the benefit of esketamine nasal spray versus real-world treatment on patient-reported functional remission: results from the ICEBERG study.

Introduction

Treatment resistant depression (TRD) affects approximately 10-30% of patients with major depressive disorder, and most patients with TRD do not respond to real-world treatments (RWT). Treatment with esketamine nasal spray (NS) plus a selective serotonin or serotonin norepinephri...
S-EPMC11491562 | biostudies-literature
TranscriptomicsGene Expression Profile of AGS cell line cultured in 2D and in 3D conditions
AGS cell line was cultured in standard T25 flasks (2D condition) and in T25 flasks precoated with 50 M-5L/cm2 of matrigel basement membrane (BD Biosciences) at a 1.5:1 proportion to RPMI serum-free medium (3D condition, overlay method). Cultures were maintained for 14 days with medium change every t...
ORGANISM(S): Homo sapiens 
2013-02-15 | E-MTAB-1234 | biostudies-arrayexpress
UnknownThe HIV type 1 epidemic in Bulgaria involves multiple subtypes and is sustained by continuous viral inflow from West and East European countries.
Little is known about the HIV-1 epidemic in Balkan countries. To fill the gap, we investigated the viral genetic diversity in Bulgaria, by sequencing and phylogenetic characterization of 86 plasma samples collected between 2002 and 2006 from seropositive individuals diagnosed within 1986-2006. Analy...
S-EPMC2927039 | biostudies-literature
UnknownICEBERG study: an indirect adjusted comparison estimating the long-term benefit of esketamine nasal spray when compared with routine treatment of treatment resistant depression in general psychiatry.

Background

Treatment resistant depression (TRD) affects 10-30% of patients with major depressive disorder. In 4-week trials, esketamine nasal spray (NS) was efficacious vs. placebo when both were initiated in addition to a new selective serotonin or serotonin norepinephrine reuptake inhibito...
S-EPMC10669153 | biostudies-literature
UnknownIndirect adjusted comparison of 6-month clinical outcomes between esketamine nasal spray and other real-world polypharmacy treatment strategies for treatment resistant depression: results from the ICEBERG study.

Background

The efficacy of esketamine nasal spray (NS) as a rapid-acting agent for treatment resistant depression (TRD) was demonstrated in comparisons with placebo, when both were given in addition to a newly initiated selective serotonin reuptake inhibitor (SSRI)/serotonin norepinephrine r...
S-EPMC10669145 | biostudies-literature
TranscriptomicsmicroRNA (miRNA) expression profiling of PBMCs of Parkinson's disease (PD) patients and controls
To investigate the role of miRNAs in the etiology of idiopathic PD, we conducted global miRNA expression profiling in peripheral blood mononuclear cells (PBMCs) of PD patients and controls. Total RNA was extracted from the PBMCs of 19 PD patients and 13 controls, labeled and hybridized to Exiqon mic...
ORGANISM(S): Homo sapiens 
2011-09-29 | E-GEOD-16658 | biostudies-arrayexpress
TranscriptomicsBlood genomic expression profile for Behçet’s disease.
Behçet’s disease (BD) is a multisystemic immuno-inflammatory disorder characterized by a generalized vasculitis, particularly at the orogenital mucosa and eye. It is a complex disease with unclear pathogenesis. To better understand BD´s etiology, we performed genomic expression profiling of patients...
ORGANISM(S): Homo sapiens 
2011-07-01 | E-GEOD-17114 | biostudies-arrayexpress
Sort   by:  
 Page size