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MetabolomicsImproving global feature detectabilities through scan range splitting for untargeted metabolomics by high-performance liquid chromatography-Orbitrap mass spectrometry
Untargeted metabolomics aims at obtaining quantitative information on the highest possible number of low-molecular biomolecules present in a biological sample. Rather small changes in mass spectrometric spectrum acquisition parameters may have a significant influence on the detectabilities of metabo...
2016-06-09 | MTBLS233 | MetaboLights
MetabolomicsMetabolome analysis via an HPLC-ESI-MS-based experimental and computational pipeline for chronic nephron toxicity profiling
Untargeted metabolomics has the potential to improve the predictivity of in vitro toxicity models and therefore may aid the reduction of expensive and laborious animal models. Here we describe a chronic nephrotoxicity study conducted on a human renal proximal tubular epithelial cell line (RPTEC/TERT...
2015-09-07 | MTBLS140 | MetaboLights
UnknownRound Robin into Best Practices for the Determination of Indentation Size Effects.
Not available
S-EPMC7022484 | biostudies-literature
ProteomicsTargeted Mass Spectrometry of a Clinically Relevant PSA Variant from Post-DRE Urines for Quantitation and Genotype Determination
The rs17632542 SNP results in lower serum PSA levels which may further mitigate against its clinical utility as a prostate cancer biomarker. Post-DRE urine is a minimally invasive fluid that is currently utilized in prostate cancer diagnosis. We have used targeted MS to detect and quantitate the v...
ORGANISM(S): Homo Sapiens 
2020-09-14 | PXD017257 | panorama
UnknownPersistence of the invasive bird-parasitic fly Philornis downsi over the host interbreeding period in the Galapagos Islands.
Not available
S-EPMC8837626 | biostudies-literature
UnknownModeling strategies for the allocation of SARS-CoV-2 vaccines in the United States.
Not available
S-EPMC8818403 | biostudies-literature
UnknownUsing the Electronic Nose to Identify Airway Infection during COPD Exacerbations.
Not available
S-EPMC4564204 | biostudies-literature
TranscriptomicsscRNAseq of freshly dissociated and cultured skin biopsies
We describe new optimised skin tissue dissociation protocol to digest ex vivo cultured and fresh human skin samples. Using scRNAseq analysis we created skin atlas composition of fresh and cultured skin samples and integrate it with other publicly available skin tissue scRNAdata to compare the qualit...
ORGANISM(S): Homo sapiens 
2022-08-04 | E-MTAB-11509 | biostudies-arrayexpress
UnknownDWV-A Lethal to Honey Bees (Apis mellifera): A Colony Level Survey of DWV Variants (A, B, and C) in England, Wales, and 32 States across the US.
Not available
S-EPMC6563202 | biostudies-literature
ProteomicsProfiling of Native and Protease_Generated Protein Amino Termini from Formalin-Fixed, Paraffin-Embedded Tissues
Dysregulated proteolysis represents a hallmark of numerous diseases. In recent years, increasing number of studies has begun looking at the protein termini in hope to unveil the physiological and pathological functions of proteases in clinical research. However, the availability of cryopreserved tis...
ORGANISM(S): Mus musculus (Mouse) 
2016-04-25 | PXD002847 | Pride
Ffpe Protease Degradome Tails Proteolysis N-terminomics 
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