Sort   by:  
 Page size 
UnknownSimulation/Experiment Confrontation, an Efficient Approach for Sensitive SAW Sensors Design.
Not available
S-EPMC7506909 | biostudies-literature
TranscriptomicsA novel class of alternative 3M-bM-^@M-^Y-terminal exons is involved in cell-cycle regulation by topoisomerase inhibitors
Alternative 3M-bM-^@M-^Y-terminal exons, which use intronic polyadenylation sites, are generally unconserved and lowly expressed, while the main gene products end in the last exon of genes. In this study, we discover a class of human genes, where the last exon appeared recently during evolution, and...
ORGANISM(S): Homo sapiens 
2014-02-04 | E-GEOD-53474 | biostudies-arrayexpress
ModelsBexkens2024 - Schistosoma mansoni glycolysis
A kinetic model of S. mansoni glycolysis in which we can vary the allosteric regulation on lactate dehydrogenase (LDH). Because not enough kinetic data are available for all the schistosome enzymes to construct a complete schistosome glycolysis model de novo, we here adjusted the well-established gl...
2024-04-04 | MODEL2208290002 | BioModels
MetabolomicsProMetIS, deep phenotyping of mouse models by combined proteomics and metabolomics analysis

Genes are pleiotropic and getting a better knowledge of their function requires a comprehensive characterization of their mutants. Here, we generated multi-level data combining phenomic, proteomic and metabolomic acquisitions from plasma and liver tissues of two C57BL/6 N mouse models lacking the...

2021-09-01 | MTBLS1903 | MetaboLights
ProteomicsUnique Leishmania mexicana clones secrete populations of extracellular vesicles with unique protein profile and variable infectious capability
The study of extracellular vesicles has become an incredibly important field of study, but the inherent heterogeneity of these vesicles continues to make their study challenging. The genetic variability and well-documented protocols for the growth and vesicle isolation from Leishmania parasites prov...
ORGANISM(S): Leishmania mexicana 
2025-05-07 | PXD058429 | Pride
Exosomes Proteomics Extracellular vesicles Infectious disease Leismania mexicana Clonal cultures 
ProteomicsProteomic Biomarkers for Leishmanial Extracellular Vesicles
Despite their clinical relevance and role in parasitic virulence, exosomes produced by the protozoan parasite Leishmania lack specific proteomic biomarkers. Herein, we utilized utilized serial differential ultracentrifugation to separate three distinct fractions of Leishmania-derived extracellular v...
ORGANISM(S): Leishmania major 
2024-06-22 | PXD048015 | Pride
Leishmaniasis Leishmania Exosome Extracellular vesicle 
ProteomicsInternalization of therapeutic antibodies into Dendritic cells as a risk factor for immunogenicity
The appended raw files, csv files and other documents were deposited into the public domain in support for the publication "Internalization of therapeutic antibodies into Dendritic cells as a risk factor for immunogenicity" by Michel Siegel, Anna-Lena Bolender, Axel Ducret, Johannes Fraidling, Katha...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-08-26 | MSV000095695 | MassIVE
UnknownCOVID-19 mass vaccination - an illustration of the impact of syringe choice on the effectiveness of mass vaccination campaigns.
Not available
S-EPMC8920360 | biostudies-literature
TranscriptomicsB-cell tumor development in Tet2-deficient mice
The TET2 gene encodes an α-ketoglutarate-dependent dioxygenase able to oxidize 5-methylcytosine into 5-hydroxymethylcytosine, which is a step toward active DNA demethylation. TET2 is frequently mutated in myeloid malignancies but also in B- and T-cell malignancies. TET2 somatic mutations are also id...
ORGANISM(S): Mus musculus 
2019-12-12 | E-MTAB-8501 | biostudies-arrayexpress
TranscriptomicsTranscript profiling in Actinobacillus pleuropneumoniae after adherence to, or planktonic growth over, SJPL cells.
Host-pathogen interactions are of great importance in understanding the pathogenesis of infectious microorganisms. We developed in vitro models to study porcine respiratory tract pathogens using an immortalized epithelial cell line, the St. Jude Porcine Lung (SJPL) cell line. In conditions where cy...
ORGANISM(S): Actinobacillus pleuropneumoniae 
2008-07-09 | E-GEOD-12009 | biostudies-arrayexpress
Sort   by:  
 Page size