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In this study, we expand on this major advancement in O-GlcNAc enrichment protocols by adapting this approach to human-banked samples, which often presents their significant challenges. Indeed, patient samples are often banked without proper washing, thus contaminating cells with abundant O-glycosyl...
ORGANISM(S): Homo sapiens (Human) 
2024-02-14 | PXD047766 | Pride
In this study, we demonstrated that OTX2 was transcriptionally and post-transcriptionally regulated by O-GlcNAcylation. We describe the modes of degradation of this essential homeobox protein involving both the proteasome and macroautophagy. While the proteasome remains the canonical degradation pat...
ORGANISM(S): Homo sapiens (Human) 
2024-01-22 | PXD040353 | Pride
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