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TranscriptomicsChanges in gene expression after epigentic targeted therapy in T-cell prolymphocytic leukemia (T-PLL)
Epigenetic therapy overcame alemtuzumab resistance in patients with relapsed T-cell prolymphocytic leukemia and induced the expression of treatment related genes. Method: patient PBMCs from Ficoll, normal patient PBMCS enriched for CD3+/CD8+ or CD3+/CD8+/CD45RA+/CCR7- were extracted in Trizol. Con...
ORGANISM(S): Homo sapiens 
2015-07-08 | E-GEOD-67368 | biostudies-arrayexpress
TranscriptomicsAndersson_et_al_2013
LGL leukemia is chronic clonal lymphoproliferative disorder, characterized by expansion of cytotoxic CD8+ T-cells or NK-cells. We compared gene expression of 2 LGL leukemia patients with STAT3 mutation (Patients 11 and 12) and 2 LGL leukemia patients without STAT3/STAT5b mutation (Patients 9 and 10)...
ORGANISM(S): Homo sapiens 
2013-11-14 | E-MTAB-2068 | biostudies-arrayexpress
UnknownHuman prostate tumor antigen-specific CD8+ regulatory T cells are inhibited by CTLA-4 or IL-35 blockade.
Not available
S-EPMC3735346 | biostudies-literature
UnknownPhase I trial of MK-0752 in children with refractory CNS malignancies: a pediatric brain tumor consortium study.
Not available
S-EPMC3179253 | biostudies-literature
UnknownOseltamivir Prophylaxis Reduces Inflammation and Facilitates Establishment of Cross-Strain Protective T Cell Memory to Influenza Viruses.
Not available
S-EPMC4473273 | biostudies-literature
UnknownAntitumor CD4+ T Helper 1 Cells Target and Control the Outgrowth of Disseminated Cancer Cells.
Not available
S-EPMC12046335 | biostudies-literature
UnknownAn efficient and robust statistical modeling approach to discover differentially expressed genes using genomic expression profiles.
Not available
S-EPMC311075 | biostudies-literature
UnknownThe JAK1 Selective Inhibitor ABT 317 Blocks Signaling Through Interferon-γ and Common γ Chain Cytokine Receptors to Reverse Autoimmune Diabetes in NOD Mice.
Not available
S-EPMC7746546 | biostudies-literature
UnknownImage familiarization sharpens response dynamics of neurons in inferotemporal cortex.
Not available
S-EPMC4613775 | biostudies-literature
TranscriptomicsGenome-wide Analyses of Diffuse Intrinsic Pontine Gliomas
Purpose: More than 90% of children with diffuse intrinsic pontine glioma (DIPG) die within 2 years of diagnosis. There is a dire need to identify therapeutic targets, however lack of patient material for research has limited progress. We evaluated a large cohort of diffuse intrinsic pontine gliomas ...
ORGANISM(S): Homo sapiens 
2011-09-20 | E-GEOD-26576 | biostudies-arrayexpress
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