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MetabolomicsLC_MS Dataset for Morin Detection in Phoebe Wood Extracts, Enzyme Assays and Transgenic Populus

This dataset contains LC-MS data generated for the detection of morin in plant tissues and enzymatic reactions related to flavonoid biosynthesis. The samples include methanol extracts of wood tissues from Phoebe species (including Phoebe zhennan and related Lauraceae species), in vitro enzyme rea...

2026-03-26 | MTBLS14137 | MetaboLights
MetabolomicsAirway Dysbiosis Accelerates Lung Function Decline in Chronic Obstructive Pulmonary Disease (Murine UPLC-MS/MS assays)

Progressive lung function decline is a hallmark of chronic obstructive pulmonary disease (COPD). Airway dysbiosis occurs in COPD, but whether it contributes to disease progression remains unknown. Here we showed, through a longitudinal analysis on two cohorts involving four UK centers, that basel...

2023-06-12 | MTBLS6894 | MetaboLights
MetabolomicsAirway Dysbiosis Accelerates Lung Function Decline in Chronic Obstructive Pulmonary Disease (Human UPLC-MS/MS assays)

Progressive decline in lung function is a hallmark of chronic obstructive pulmonary disease (COPD). Although airway dysbiosis occurs in COPD, whether it contributes to disease progression remains unknown. Here, through a longitudinal analysis on 181 COPD individuals from two large cohorts involvi...

2023-06-12 | MTBLS5423 | MetaboLights
MetabolomicsBioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative (Streptococcus pneumoniae assays)

The Antibiotic Resistant Sepsis Pathogens Framework Initiative aims to develop a framework dataset of 5 sepsis pathogens (5 strains each) using an integrated application of genomic, transcriptomic, metabolomic and proteomic technologies. The pathogens included in this initiative are: Escheric...

2022-08-03 | MTBLS2323 | MetaboLights
MetabolomicsMechanistic insights into the biological activity of S-Sulfocysteine in CHO cells using a multi-omics approach
S-Sulfocysteine (SSC), a bioavailable L-cysteine derivative (Cys), is known to be taken up and metabolized in Chinese hamster ovary (CHO) cells used to produce novel therapeutic biological entities. To gain a deeper mechanistic insight into the SSC biological activity and metabolization, a multi-omi...
2024-08-08 | MTBLS7424 | MetaboLights
MetabolomicsCritical shifts in lipid metabolism promote megakaryocyte differentiation and proplatelet formation (Shotgun lipidomics assays without inhibition)

During megakaryopoiesis, megakaryocytes (MK) undergo cellular morphological changes with strong modification of membrane composition and lipid signaling. Here we adopt a lipid-centric multi-omics approach to create a quantitative map of the MK lipidome during maturation and proplatelet formation....

2023-07-26 | MTBLS6082 | MetaboLights
MetabolomicsMulti-omics Mechanistic Analysis of Efficient Lignocellulose Degradation by Pholiota adiposa Strain YAHS

Abstract This study focused on elucidating the lignocellulose degradation mechanism of Pholiota adiposa strain YAHS, aiming to provide theoretical basis and microbial resources for straw biorefining. Using the aniline blue-guaiacol plate screening method, 11 fungal strains were isolated from the ...

2025-10-12 | MTBLS13121 | MetaboLights
MetabolomicsExploring the molecular intersection for hypertension, hyperlipidemia and their comorbid conditions through multi-omics approaches

Abstract

Background: Hypertension and hyperlipidemia are interconnected conditions that heighten cardiovascular risk, yet their intricate multi-scale molecular signatures remain inadequately mapped. This study aimed to conduct an integrated multi-omics investigation to unravel the key pathw...

2025-09-25 | MTBLS13039 | MetaboLights
MetabolomicsExploring the mechanism of YJW's antidepressant effect based on multi omics analysis

Exploring the mechanism of YJW's antidepressant effect based on multi omics analysis.

Exploring the mechanism of YJW's antidepressant effect based on multi omics analysis

Exploring the mechanism of YJW's antidepressant effect based on multi omics analysis

2026-10-05 | MTBLS15921 | MetaboLights
MetabolomicsCritical shifts in lipid metabolism promote megakaryocyte differentiation and proplatelet formation (Shotgun lipidomics assays after inhibition with FSG67 and Triacsin C)

During megakaryopoiesis, megakaryocytes (MK) undergo cellular morphological changes with strong modification of membrane composition and lipid signaling. Here we adopt a lipid-centric multi-omics approach to create a quantitative map of the MK lipidome during maturation and proplatelet formation....

2023-07-26 | MTBLS6083 | MetaboLights
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