Sort   by:  
 Page size 
ProteomicsONECUT2 acts a lineage plasticity driver
Androgen receptor- (AR-) indifference is a mechanism of resistance to hormonal therapy in prostate cancer (PC). Here we demonstrate that ONECUT2 (OC2) activates resistance through multiple drivers associated with adenocarcinoma, stem-like and neuroendocrine (NE) variants. Direct OC2 gene targets inc...
ORGANISM(S): Homo sapiens (Human) 
2024-08-10 | PXD050634 | Pride
Onecut2 Prostate cancer Interactome Lc-ms/ms 
GenomicsGene expression microarrays of ONECUT2-overexpression in human pancratic islets
Gene expression microarrays of ONECUT2-overexpression in human pancratic islets
PRJNA1422108 | ENA
UnknownONECUT2 overexpression promotes RAS-driven lung adenocarcinoma progression.
Not available
S-EPMC6934839 | biostudies-literature
UnknownONECUT2 facilitates hepatocellular carcinoma metastasis by transcriptionally upregulating FGF2 and ACLY.
Not available
S-EPMC8627506 | biostudies-literature
UnknownONECUT2 is a driver of neuroendocrine prostate cancer.
Not available
S-EPMC6336817 | biostudies-literature
GenomicsONECUT2 Drives Neuroendocrine Prostate Cancer Through Hypoxia Signaling
ONECUT2 Drives Neuroendocrine Prostate Cancer Through Hypoxia Signaling
PRJNA416257 | ENA
GenomicsIncreased ONECUT2 induced by Helicobacter pylori promotes gastric cancer cell stemness via AKT-related pathway
Increased ONECUT2 induced by Helicobacter pylori promotes gastric cancer cell stemness via AKT-related pathway
PRJNA1110770 | ENA
UnknownThe homeodomain regulates stable DNA binding of prostate cancer target ONECUT2.
Not available
S-EPMC11490551 | biostudies-literature
TranscriptomicsONECUT2 overexpression promotes RAS-driven lung adenocarcinoma progression
Aberrant differentiation, driven by activation of normally silent tissue-specific genes, results in a switch of cell identity and often leads to cancer progression. The underlying genetic and epigenetic events are largely unexplored. Here, we report ectopic activation of the hepatobiliary-, intestin...
ORGANISM(S): Homo sapiens 
2019-12-27 | GSE102599 | GEO
UnknownIncreased ONECUT2 induced by Helicobacter pylori promotes gastric cancer cell stemness via an AKT-related pathway.
Not available
S-EPMC11245518 | biostudies-literature
Sort   by:  
 Page size