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TranscriptomicsTranscription profiling of mouse CD4+ T cells gene-transduced with AML1, wild type Foxp3, and a Foxp3 mutant defective in binding to AML1
To clarify how Foxp3 regulates its target genes, we performed co-immunoprecipitation experiments and found that Foxp3 physically bound to AML1/Runx1 (Ono, M. et al, Nature, 2007). In this series of study, we compared gene regulations by AML1, wild type Foxp3, and a Foxp3 mutant with defective bindin...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-6939 | biostudies-arrayexpress
TranscriptomicsMicroarray analysis of FoxP3-expressing or non-expressing subsets of human CD4+ T cells
Gene expression profiles of subsets of CD4+ T cells according to their expression of FoxP3 and CD45RA were compared. Abstract: FoxP3 is a key transcription factor for the development and function of natural CD4+ regulatory T cells (Tregs). Here we show that human FoxP3+CD4+ T cells are composed of...
ORGANISM(S): Homo sapiens 
2009-05-21 | E-GEOD-15659 | biostudies-arrayexpress
TranscriptomicsIdentification of EP4 as a Potential Target for the Treatment of Castration-Resistant Prostate Cancer Using a Novel Xenograft Model
More effective therapeutic approaches for castration-resistant prostate cancer (CRPC) are urgently needed, thus reinforcing the need to understand how prostate tumors progress to castration resistance. We have established a novel mouse xenograft model of prostate cancer, KUCaP-2, which expresses the...
ORGANISM(S): Homo sapiens 
2010-06-08 | E-GEOD-21887 | biostudies-arrayexpress
UnknownDNA demethylation by ROS1a in rice vegetative cells promotes methylation in sperm.
Not available
S-EPMC6511055 | biostudies-literature
UnknownAssociation of patient quality of life with the degree of agreement in the perceptions of patient disability within the stroke patient-rehabilitation therapist dyad: a cross-sectional study in postdischarge rehabilitation setting.
Not available
S-EPMC8103374 | biostudies-literature
TranscriptomicsTranscription profiling of Coturnix japonica during the photoinduction process.
The molecular mechanism of photoperiodic time measurement remains unknown in animals. Japanese quail is an excellent model for studying these phenomena because of their rapid and dramatic response to photoperiod. When quail are transferred from short to long day conditions, increase in plasma gonado...
ORGANISM(S): Coturnix japonica 
2008-11-06 | E-GEOD-8017 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of chicken and Japanese quail
Since Japanese quail and chicken belong to the same order Galliforms, DNA sequence of both species are highly conserved and proved to be applicable for various analyses each other. Quail are commonly used to address physiological questions for reasons of economy. To test whether chicken microarrays ...
ORGANISM(S): Coturnix japonica 
2008-11-06 | E-GEOD-8016 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of quail MBH under short and long day conditions.
Various physiological processes and behaviours are controlled by changing daylength. To dissect genes involved in the photoperiodic changes in physiology and behaviour, global expression analysis was performed using quail kept under short and long day conditions. Experiment Overall Design: The medio...
ORGANISM(S): Coturnix japonica 
2008-11-06 | E-GEOD-8018 | biostudies-arrayexpress
UnknownEffect of an Introduced Phytoene Synthase Gene Expression on Carotenoid Biosynthesis in the Marine Diatom Phaeodactylum tricornutum.
Not available
S-EPMC4557025 | biostudies-literature
UnknownThe 2023 Guidelines for the management and treatment of glucocorticoid-induced osteoporosis.
Not available
S-EPMC10982086 | biostudies-literature
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