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MetabolomicsResolvin E1 in follicular fluid acts as a potential biomarker and improves oocyte developmental competence by optimizing cumulus cells

The metabolic profile of follicular fluid (FF) has been investigated to look for biomarkers for oocyte quality. Resolvin E1 (RvE1), a potent pro-resolving mediator, was reported to have protective action in cell function. The study aimed to examine the predictive value of RvE1 for oocyte quality ...

2020-03-26 | MTBLS1488 | MetaboLights
ProteomicsA proteomic signature of oocyte quality from models of varying oocyte developmental competence
Within the ovarian follicle, mammalian oocytes acquire the necessary molecular machinery for successful fertilisation and embryonic development. In the absence of the follicle, oocytes matured in vitro (IVM) using traditional IVM show compromised developmental competence, resulting in poorer outcome...
ORGANISM(S): Mus musculus (Mouse) 
2026-08-24 | PXD073269 | Pride
Capacitation-ivm (capa-ivm) Assisted reproductive technologies Folliculogenesis Oocyte Cumulus cell In vitro maturation (ivm) 
TranscriptomicsTranscriptome based identification of mouse cumulus cell markers that predict the developmental competence of their enclosed antral oocytes
The cumulus cells (CCs) that envelope antral and ovulated oocytes have been regarded as putative source of non-invasive markers of the oocyte developmental competence and a number of studies have observed a correlation between CCs gene expression, embryo quality and final pregnancy outcome. With the...
ORGANISM(S): Mus musculus 
2013-09-01 | E-GEOD-46906 | biostudies-arrayexpress
TranscriptomicsDifferentiating factors of cumulus cells related to quality of the human oocyte [CadoretPart3]
Our aim was to identify at the level of cumulus cells any genes related to oocyte developmental competence 2-condition experiment: blastocyst (B) AND embryo of poor quality (E).
ORGANISM(S): Homo sapiens 
2012-12-10 | E-GEOD-37116 | biostudies-arrayexpress
TranscriptomicsDifferentiating factors of cumulus cells related to quality of the human oocyte
Single embryo transfer (SET) is the most successful way to reduce the frequency of multiple pregnancies during in vitro fertilisation. However, selecting the embryo with the highest chances of pregnancy for SET remains a difficult challenge, since morphological and kinetics criteria provide poor pre...
ORGANISM(S): Homo sapiens 
2012-12-10 | E-GEOD-37277 | biostudies-arrayexpress
TranscriptomicsDifferentiating factors of cumulus cells related to quality of the human oocyte [CadoretPart2]
Our aim was to identify at the level of cumulus cells any genes related to oocyte developmental competence 2-condition experiment: blastocyst (B) ans embryo of poor quality (E).
ORGANISM(S): Homo sapiens 
2012-12-10 | E-GEOD-37117 | biostudies-arrayexpress
TranscriptomicsDifferentiating factors of cumulus cells related to quality of the human oocyte [CadoretPart1]
Our aim was to identify at the level of cumulus cells any genes related to oocyte developmental competence three-condition experiment: blastocyst (B), embryo of poor quality (E) AND immature oocytes (VG).
ORGANISM(S): Homo sapiens 
2012-12-10 | E-GEOD-37110 | biostudies-arrayexpress
GenomicsOocyte developmental competence is instructed by H3.3 chaperone Hira complex
Oocyte developmental competence is instructed by H3.3 chaperone Hira complex
PRJNA612309 | ENA
GenomicsMiRNA expression profile in relation to oocyte developmental competence
MiRNA expression profile in relation to oocyte developmental competence
PRJNA503193 | ENA
TranscriptomicsEffects of in vitro maturation on oocyte gene expression
In vitro oocyte maturation (IVM) holds great promise as a tool for enhancing clinical treatment of infertility, enhancing availability of non human primates for development of disease models, and facilitating endangered species preservation. However, IVM outcomes have remained significantly below s...
ORGANISM(S): Macaca mulatta 
2009-05-20 | E-GEOD-11895 | biostudies-arrayexpress
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