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MetabolomicsDifferent dose exposure of OPC-163493 on HepG2 cells (part-I)
Not available
ORGANISM(S): Homo sapiens 
ST001135 | MetabolomicsWorkbench
MetabolomicsMetabolme analysis of OPC-163493 on the Liver of ZDF rats (part-II)
Not available
ORGANISM(S): Rattus norvegicus 
ST001136 | MetabolomicsWorkbench
TranscriptomicsExpression profile of OPC senescence
To identify factors involved in OPC senescence, we compared gene expressions between OPC-CG4, OPC-FCS and OPC-Rev. We established OPC senescence model system, in which OPC become senescent in the presence of high concentration of FCS. This phenotypes were kept even when the medium was switched to th...
ORGANISM(S): Mus musculus 
2011-06-01 | E-GEOD-28093 | biostudies-arrayexpress
MetabolomicsAntidiabetic and cardiovascular beneficial effects of a liver-localized mitochondrial uncoupler
Inducing mitochondrial uncoupling (mUncoupling) is an attractive therapeutic strategy for treating metabolic diseases because it leads to calorie-wasting by reducing the efficiency of oxidative phosphorylation (OXPHOS) in mitochondria. Here we report a safe mUncoupler, OPC-163493, which has unique p...
2019-05-24 | MTBLS836 | MetaboLights
TranscriptomicsComprehensive Identification of Long Non-coding RNAs in Purified Cell Types from the Brain Reveals Functional LncRNA in OPC Fate Determination (RNA-Seq of differentiated NSC after lnc-OPC knockdown)
To quantitative analysis of transcriptome changes caused by lnc-OPC knockdown during OPC differentiation from NSC, lentivirus-based short hairpin RNAs were used to knockdown the lnc-OPC expression in a neural stem cell culture . Subsequently, puromycin-selected NSCs were differentiated to OPC in cul...
ORGANISM(S): Mus musculus 
2015-11-04 | E-GEOD-74647 | biostudies-arrayexpress
ProteomicsAstrocyte, OPC, OL in rat postnatal development
Proteomic analysis of astrocyte, OPC, OL isolated from postnatal day 5 rat.
ORGANISM(S): Rattus Norvegicus 
2022-05-03 | PXD033729 |
GenomicsEffect of slit1 gene overexpression during opc differentiation
Effect of slit1 gene overexpression during opc differentiation
PRJNA1152250 | ENA
TranscriptomicsExpression profile of OPC senescence
To identify factors involved in OPC senescence, we compared gene expressions between OPC-CG4, OPC-FCS and OPC-Rev.
ORGANISM(S): Mus musculus 
2011-06-01 | GSE28093 | GEO
ProteomicsLPC 18:1 protein interaction (OPC)
Oligodendrocyte progenitor cells (OPC) were cultured in the presence of LPC 18:1-Cy5. Proteins interacting with LPC 18:1-Cy5 were UV crossed linked and cell lysates were separated via isoelectric focusing gel electrophoresis. Band was cut out from gel and processed for mass spectrometry. OPC lysates...
ORGANISM(S): Mus musculus (Mouse) 
2022-02-17 | PXD025175 | Pride
Liposome floatation assay Protein-lipid complex Lpc 18:1-cy5 Lpc 18:1 
GenomicsAnalysis of gene expression in primary murine OPC isolated from cerebrum and spinal cord to identify differentially regulated genes important for OPC migration
Analysis of gene expression in primary murine OPC isolated from cerebrum and spinal cord to identify differentially regulated genes important for OPC migration
PRJNA738451 | ENA
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