Sort   by:  
 Page size 
ProteomicsProfiling the diversity of agonist-selective effects on the proximal proteome environment of G protein-coupled receptors
G protein-coupled receptors (GPCRs) regulate many aspects of physiology and represent actionable targets for drug discovery. Activation of specific signaling pathways downstream of G-protein coupled receptors (GPCRs) or targeting the receptors at selected cellular locations has the potential to prov...
ORGANISM(S): Homo sapiens (Human) 
2024-03-30 | PXD031415 | Pride
Ap-ms Mu opioid receptor Dia Apex Gpcr Dda 
ProteomicsAntagonism of the Mu-Delta Opioid Receptor Heterodimer Enhances Opioid Anti-Nociception by Activating Src and CaMKII Signaling
The opioid receptors are important regulators of pain, reward, and addiction. Limited evidence suggests the mu and delta opioid receptors form a heterodimer (MDOR), which may act as a negative feedback brake on opioid-induced analgesia. However, evidence for the MDOR in vivo is indirect and limited,...
ORGANISM(S): Mus musculus (Mouse) 
2023-03-10 | PXD022106 | Pride
Opiod mdor oxymorphone nociception 
UnknownOpioid receptors signaling network.
Not available
S-EPMC9411393 | biostudies-literature
ProteomicsProfiling the diversity of agonist-selective effects on the proximal proteome environment of G protein-coupled receptors
G-protein coupled receptors (GPCRs) regulate various aspects of cellular behavior and represent actionable targets for drug discovery. Activation of specific signaling pathways downstream of G-protein coupled receptors (GPCRs) or targeting the receptors at selected cellular locations has the potenti...
ORGANISM(S): Homo Sapiens 
2024-03-31 | PXD031393 | panorama
UnknownOpioid Receptors and Protonation-Coupled Binding of Opioid Drugs.
Not available
S-EPMC8707250 | biostudies-literature
UnknownThe evolution of vertebrate opioid receptors.
Not available
S-EPMC3070387 | biostudies-literature
UnknownRegulation of Opioid Receptors by Their Endogenous Opioid Peptides.
Not available
S-EPMC8277103 | biostudies-literature
UnknownEvolution of vertebrate opioid receptors.
Not available
S-EPMC2563095 | biostudies-literature
UnknownThe orphan receptor GPR88 blunts the signaling of opioid receptors and multiple striatal GPCRs.
Not available
S-EPMC7012601 | biostudies-literature
UnknownEnkephalin Disinhibits Mu Opioid Receptor-Rich Striatal Patches via Delta Opioid Receptors.
Not available
S-EPMC4698909 | biostudies-literature
Sort   by:  
 Page size