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To study the relationship between microRNAs and μ-opioid receptor (MOR) signaling, we examined microRNA expression after chronic morphine or fentanyl treatment in rat primary hippocampal neurons and in mouse hippocampus. Mouse cerebellum region was also tested as a negative control to eliminate mic...
ORGANISM(S): Homo sapiens 
Endogenous opioid signalling regulates spinal ependymal cell proliferation
After injury, mammalian spinal cords develop scars to confine the lesion and prevent further damage. However, excessive scarring can hinder neural regeneration and functional recovery. These competing actions underscore the importance of developing therapeutic strategies to dynamically modulate scar...
ORGANISM(S): Mus musculus 
2024-06-29 | GSE255883 | GEO
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