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ProteomicsHLA-DR15 Molecules Jointly Shape an Autoreactive T Cell Repertoire in Multiple Sclerosis
Autoimmune diseases are often associated with HLA molecules. Multiple sclerosis (MS) is a prototypical example with the HLA-DR15 haplotype as strongest genetic factor. How it contributes to MS is not clear, but key to understand this and other autoimmune diseases. Autoreactive CD4+ T cells and proin...
ORGANISM(S): Homo sapiens (Human) 
2020-10-22 | PXD015249 | Pride
Multiple sclerosis Hla cross-restriction Immunopeptidome B cells Hla-dr-derived self-peptides Cross-reactivity Hla-dr15 molecules Autoreactive cd4+ t cells 
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