Sort   by:  
 Page size 
TranscriptomicsCharacterization of Gene Expression in ASS1-Deficient Breast Cancer Cells
Analysis of mechanism underlying the metabolic effects of ADI-PEG20 at gene expression level. The hypothesis tested in the present study was that ASS1-deficient breast cancer cells would be arginine-auxotrophs and would therefore be sensitive to arginine starvation. Results provide important informa...
ORGANISM(S): Homo sapiens 
2014-05-20 | E-GEOD-53838 | biostudies-arrayexpress
MetabolomicsMetabolic Effects of a Chronic Dietary Exposure to a Low-Dose Pesticide Cocktail in Mice: Sexual Dimorphism and Role of the Constitutive Androstane Receptor (Untargeted urine UPLC-MS assay)
BACKGROUND: Epidemiological evidence suggests a link between pesticide exposure and the development of metabolic diseases. However, most experimental studies have evaluated the metabolic effects of pesticides using individual molecules, often at non relevant doses or in combination with other r...
2019-05-28 | MTBLS596 | MetaboLights
UnknownCitrulline and ADI-PEG20 reduce inflammation in a juvenile porcine model of acute endotoxemia.
Not available
S-EPMC11338849 | biostudies-literature
UnknownA Phase II Study of Arginine Deiminase (ADI-PEG20) in Relapsed/Refractory or Poor-Risk Acute Myeloid Leukemia Patients.
Not available
S-EPMC5595917 | biostudies-literature
UnknownPhase 1 trial of ADI-PEG20 plus cisplatin in patients with pretreated metastatic melanoma or other advanced solid malignancies.
Not available
S-EPMC8076217 | biostudies-literature
MetabolomicsMetabolic Effects of a Chronic Dietary Exposure to a Low-Dose Pesticide Cocktail in Mice: Sexual Dimorphism and Role of the Constitutive Androstane Receptor (Untargeted urine, plasma and liver NMR assay)
BACKGROUND: Epidemiological evidence suggests a link between pesticide exposure and the development of metabolic diseases. However, most experimental studies have evaluated the metabolic effects of pesticides using individual molecules, often at non-relevant doses or in combination with other r...
2018-05-01 | MTBLS602 | MetaboLights
UnknownEfficacy of arginine depletion by ADI-PEG20 in an intracranial model of GBM.
Not available
S-EPMC6294248 | biostudies-literature
MetabolomicsGrowth control of the eukaryote cell: a systems biology study in yeast
Metabolic control analysis is being exploited in a systems biology study of the eukaryotic cell. Using chemostat culture, we have measured the impact of changes in flux (growth rate) on the transcriptome, proteome, endometabolome and exometabolome of the yeast Saccharomyces cerevisiae. Each function...
2012-04-19 | MTBLS8 | MetaboLights
UnknownPhase I study of ADI-PEG20 plus low-dose cytarabine for the treatment of acute myeloid leukemia.
Not available
S-EPMC8085967 | biostudies-literature
UnknownDiscovery and Targeting of a Noncanonical Mechanism of Sarcoma Resistance to ADI-PEG20 Mediated by the Microenvironment.
Not available
S-EPMC10425734 | biostudies-literature
Sort   by:  
 Page size