Oral cavity squamous cell carcinoma

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Organisms

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human oral metagenome (1)

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Tissue

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Uterus (1)

Disease

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Cecum carcinoma (1)
Cervical adenocarcinoma (1)
Cervical carcinoma (1)
Cervical squamous cell carcinoma (1)
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Chronic myelogenous leukemia (1)
Colon adenocarcinoma (1)
Colon carcinoma (1)
Ewing's sarcoma (1)
Hodgkin's lymphoma (1)

Technology Type

Mass Spectrometry (19)
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Mass spectrometry (3)
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454 GS FLX Titanium, Illumina HiSeq 2000 (1)
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Instrument Platform

LTQ Orbitrap Velos (4)
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Gas Chromatography MS - positive (2)
NextSeq 2000 (1)
Illumina HiSeq 2500 (1)
Illumina HiSeq 4000 (1)
Illumina CanineHD (1)
- (1)
Instrument (1)
LTQ Orbitrap (1)
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Liquid Chromatography MS - positive - hilic (1)

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2013 (35)
2012 (24)
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2007 (5)
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2005 (2)
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2006 (1)

CHEBI ID

CHEBI:16199 (2)
CHEBI:15971 (2)
CHEBI:17295 (2)
CHEBI:15428 (2)
CHEBI:17509 (2)
CHEBI:16335 (2)
CHEBI:16027 (2)
CHEBI:17191 (2)
CHEBI:30769 (2)
CHEBI:15676 (2)
CHEBI:29985 (1)
CHEBI:91242 (1)
CHEBI:192870 (1)
CHEBI:91114 (1)
CHEBI:183826 (1)
CHEBI:43987 (1)
CHEBI:192970 (1)
CHEBI:192969 (1)
CHEBI:131360 (1)
CHEBI:131420 (1)
CHEBI:192968 (1)
CHEBI:89676 (1)
CHEBI:79839 (1)
CHEBI:24577 (1)
CHEBI:192971 (1)
CHEBI:84290 (1)
CHEBI:191953 (1)
CHEBI:77517 (1)
CHEBI:55381 (1)
CHEBI:88105 (1)

Metabolite Name

Leucine (3)
Nicotianamine (2)
Valine (2)
Spermidine (2)
Urea (2)
Xanthosine (2)
Thymine (2)
Nicotinamide (2)
Lysine (2)
Glycine (2)
Glycerol (2)
Taurine (2)
Phenol (2)
Hypoxanthine (2)
Adenine (2)
Xanthine (2)
Guanosine (2)
Inosine (2)
Isoleucine (2)
Oleamide (2)
Creatinine (2)
Histidine (2)
Phenylalanine (2)
Guanine (2)
Creatine (2)
Adenosine (2)
Isoleuscine (1)
Beta- Glucose (1)
M3 3-Phosphoglycerate (1)
M2 3-Phosphoglycerate (1)

First Public Date

2025 (12)
2022 (10)
2014 (10)
2024 (8)
2023 (8)
2021 (8)
2026 (7)
2017 (4)
2019 (3)
2018 (3)
2020 (2)
2016 (1)
2015 (1)
2013 (1)

Study status

Completed (6)
Active, not recruiting (1)

Study type

Transcription profiling by array (115)
Comparative genomic hybridization by array (18)
Methylation profiling by array (16)
RNA-seq of coding RNA (10)
Interventional (7)
RNA-seq of non coding RNA (3)
Transcription profiling by SAGE (2)
Genotyping by array (2)
MicroRNA profiling by high throughput sequencing (2)
MicroRNA profiling by array (2)
DNA-seq (2)
Cell line - High-throughput sequencing (1)
Transcription profiling by RT-PCR (1)
Spatial transcriptomics by high-throughput sequencing (1)
RNA-seq of coding RNA from single cells (1)
Methylation profiling by high throughput sequencing (1)

Release Date

2024 (169)
2023 (82)
2022 (81)
2021 (74)
2020 (73)
2025 (63)
2019 (50)
2016 (45)
2015 (42)
2013 (42)
2014 (39)
2017 (36)
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2011 (27)
2012 (26)
2026 (14)
2010 (13)
2008 (13)
2009 (7)
2007 (5)
2006 (4)
2005 (1)
2002 (1)
1997 (1)

Lab affiliation

Department of Medical Biotechnology and Laboratory Science College of Medicine, Chang Gung University, Taoyuan, Taiwan (2)
9McKusick-Nathans Institute of Genetic Medicine, 10Departments of Biological Chemistry, and 11Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. (1)
Amsterdam UMC, Vrije Universiteit Amsterdam, Medical Oncology, Cancer Center Amsterdam, OncoProteomics Laboratory, Amsterdam, Netherlands (1)
Bavarian Center for Biomolecular Mass Spectrometry at Klinikum rechts der Isar (BayBioMS@MRI), TUM School of Medicine and Health, Technical University of Munich (TUM), 81675 München, Germany (1)
Chang Gung University Department of Medical Biotechnology and Laboratory Science (1)
Department of Biophysics,All India Institute of MedicalSciences, New Delhi, India (1)
Department of Medical Biotechnology and Laboratory Science, College of Medicine, Chang Gung University, Taiwan (1)
Department of Medical Biotechnology and Laboratory Sciences, College of Medicine, Chang Gung University, Taiwan (1)
Head of Mass Spectrometry Laboratory, Brazilian Biosciences National Laboratory (LNBio), Brazilian Center for Research in Energy and Materials (CNPEM), Campinas, SP, Brazil. (1)
Institute of Bioinformatics, Bangalore (1)
Institute of Bioinformatics, ITPB, Bangalore, India (1)
Laboratório Nacional de Biociências, LNBio, CNPEM, Campinas, São Paulo, 13083-970, Brazil (1)
Laboratório de Espectrometria de Massas, Laboratório Nacional de Biociências, LNBio, CNPEM, Campinas, SP, Brazil. (1)
Professor and Deputy Director, Center for Systems Biology and Molecular Medicine Yenepoya Research Centre, Yenepoya (Deemed to be University) Mangalore, India (1)
Project investigatior, institute of bioinformatics, Bangalore, Inida Project advisor,Mazumdar Shaw Center for Translational Research, Bangalore,India (1)
Spatial Proteomics Lab, Max Delbrück Center für Molekulare Medizin, Berlin, Germany (1)
University Medicine Greifswald Interfaculty Institute for Genetics and Functional Genomics Department of Functional Genomics Friedrich-Ludwig-Jahn-Str. 15a 17475 Greifswald, Germany (1)
Washington University in St. Louis (1)

Location

United States (6)
Guam (1)
Japan (1)

Keyword

Antineoplastic Agents, Immunological (3)
Antibodies (3)
Immunoglobulins (3)
Antibodies, Monoclonal (3)
Cetuximab (3)
Erlotinib Hydrochloride (2)
7-hydroxystaurosporine (1)
Interleukin-12 (1)
Albumin-Bound Paclitaxel (1)
Lenalidomide (1)
Carboplatin (1)
Nivolumab (1)
Ipilimumab (1)
Trastuzumab (1)
Irinotecan (1)
Bevacizumab (1)

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System Xc- exacerbates metabolic stress under glucose depletion in oral squamous cell carcinoma

OBJECTIVE: Emerging evidence suggests that glucose depletion (GD)-induced cell death depends on system Xc-, a glutamate/cystine antiporter extensively studied in ferroptosis. However, the underlying mechanism remains debated. Our study confirmed the correlation between system Xc...

2024-01-16 | MTBLS5358 | MetaboLights

Mechanistic study of the effects of salivary components from OSCC patients on tumor growth using a mouse model of oral squamous cell carcinoma

2025-08-01 | MTBLS12805 | MetaboLights

Transcription profiling of oral cavity samples from human squamous cell carcinoma patients

Metastasis via the lymphatics is a major risk factor in squamous cell carcinoma of the oral cavity (OSCC). We sought to determine whether the presence of metastasis in the regional lymph node could be predicted by a gene expression signature of the primary tumor. A total of 18 OSCCs were characteriz...

ORGANISM(S): Homo sapiens

2007-08-25 | E-GEOD-2280 | biostudies-arrayexpress

Expression data from oral squamous cell carcinoma (OSCC)-derived cell lines and normal oral keratinocytes

Oral squamous cell carcinoma (OSCC) is a lethal disease and early death usually occurs as a result of local invasion and regional lymph node metastases. We used microarrays to identify down or upregulated genes in OSCCs compared with non-malignant controls. To identify genes whose transcription is d...

ORGANISM(S): Homo sapiens

2011-09-01 | E-GEOD-31853 | biostudies-arrayexpress

Expression and SNP array data for oral squamous cell carcinoma

This SuperSeries is composed of the following subset Series: GSE25099: Expression data from 57 patients with oral cancer and 22 normal persons GSE25103: Affymetrix SNP array data for oral squamous cell carcinoma Refer to individual Series

ORGANISM(S): Homo sapiens

2011-08-31 | E-GEOD-25104 | biostudies-arrayexpress

Development of a potential salivary biomarker panel for Oral Squamous Cell Carcinoma using a proteomics-based approach.

Oral Squamous Cell Carcinoma (OSCC) is one of the most prevalent cancers in the world with the maximum number of cases reported from India. Poor survival rate associated with OSCC can be attributed to the non-availability of a biomarker, as one of the major reasons, leading to late presentation. Ide...

ORGANISM(S): Homo Sapiens

2021-07-09 | PXD020263 | panorama

NID2 and HOXA9 promoter hypermethylation as biomarkers to prevent and detect Oral Cavity Squamous Cell Carcinoma

Differentially methylated oral squamous cell carcinoma (OSCC) biomarkers, identified in-vitro and validated in well-characterized surgical specimens, have shown poor clinical correlation in cohorts with different risk profiles. To overcome this lack of relevance we used the HumanMethylation27 BeadCh...

ORGANISM(S): Homo sapiens

2013-02-13 | E-GEOD-28217 | biostudies-arrayexpress

A YAP/TAZ-Regulated Molecular Signature is Associated with Oral Squamous Cell Carcinoma

Oral squamous cell carcinoma (OSCC) is a prevalent form of cancer that develops from the epithelium of the oral cavity. OSCC is on the rise worldwide, and death rates associated with the disease are particularly high. Despite progress in understanding of the mutational and expression landscape assoc...

ORGANISM(S): Homo sapiens

2015-05-26 | E-GEOD-66949 | biostudies-arrayexpress

Biomarker Discovery in Oral Cancer (OSMF & OSCC) and its severity

Oral squamous cell carcinoma (OSCC) is frequently the outcome of oral submucous fibrosis (OSMF), a common possibly premalignant disease. In our study, a cohort of 50 patients with OSCC and OSMF, along with 50 healthy controls, was analyzed to identify significant metabolic differences between the...

2024-10-23 | MTBLS11009 | MetaboLights

OSCC Illumina GoldenGate Methylation

This study aims to compare the DNA methylome across a large cohort of oral squamous cell carcinoma and matched normal samples. DNA from 44 OSCCs and paired normal mucosa were analysed using Illumina GoldenGate methylation array. This data was correlated with extracapsular spread (extracapsular sprea...

ORGANISM(S): Homo sapiens

2013-08-02 | E-MTAB-1298 | biostudies-arrayexpress

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OBJECTIVE: Emerging evidence suggests that glucose depletion (GD)-induced cell death depends on system Xc-, a glutamate/cystine antiporter extensively studied in ferroptosis. However, the underlying mechanism remains debated. Our study confirmed the correlation between system Xc...

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