Sort   by:  
 Page size 
ProteomicsAgonists of orally expressed TRP channels stimulate salivary secretion and modify the salivary proteome
Natural compounds that can stimulate salivary secretion are of interest in developing treatments for xerostomia, the perception of a dry mouth, that affects between 10 and 30% of the adult and elderly population. Chemesthetic transient receptor potential (TRP) channels are expressed in the surface ...
ORGANISM(S): Homo sapiens (Human) 
2020-07-16 | PXD017232 | Pride
Menthol Proteome Transient receptor potential channel agonists Nonivamide Saliva Cinnamaldehyde 
UnknownTetrathiomolybdate inhibits copper trafficking proteins through metal cluster formation.
Not available
S-EPMC3658115 | biostudies-literature
UnknownLmo1656 is a secreted virulence factor of Listeria monocytogenes that interacts with the sorting nexin 6-BAR complex.
Not available
S-EPMC6005434 | biostudies-literature
UnknownAgonists of Orally Expressed TRP Channels Stimulate Salivary Secretion and Modify the Salivary Proteome.
Not available
S-EPMC8014997 | biostudies-literature
UnknownHepatocyte-secreted DPP4 in obesity promotes adipose inflammation and insulin resistance.
Not available
S-EPMC6021131 | biostudies-literature
ProteomicsSECRETOME DATA only from “Selective stalling of human translation through small molecule engagement of the ribosome nascent chain”
Human genetics as well as pharmacological intervention reveal that Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) plays a key role in regulating the levels of plasma low density lipoprotein cholesterol (LDL-C). Here we demonstrate that the compound PF-06446846 inhibits translation of PCSK9 by...
ORGANISM(S): Homo sapiens (Human) 
2017-03-27 | PXD005822 | Pride
Translational stalling Cell lysate Silac Pcsk9 Huh7 cells Secretome 
MetabolomicsAkkermansia muciniphila secretes a glucagon-like peptide-1-inducing protein that improves glucose homeostasis and ameliorates metabolic disease
The gut microbiome is a key factor regulating energy-metabolism, glucose tolerance and the immune system. Akkermansia muciniphila has been identified as being beneficial gut bacterium for metabolic diseases, including obesity and type 2 diabetes (T2D); however, the molecular mechanisms involved in h...
2021-01-13 | MTBLS1824 | MetaboLights
TranscriptomicsTranscription profiling of mouse small intestine in the development of dietary fat-induced obesity and insulin resistance in C57BL/6J strain.
Obesity and insulin resistance are two major risk factors underlying the metabolic syndrome. To gain more insight in the role of the small intestine in the etiology of these metabolic disorders, a microarray study was performed on small intestines (SI) of C57BL/6J mice that were fed a high fat diet ...
ORGANISM(S): Mus musculus 
2008-06-20 | E-GEOD-8582 | biostudies-arrayexpress
ProteomicsCELL LYSATE DATA only from “Selective stalling of human translation through small molecule engagement of the ribosome nascent chain”
Human genetics as well as pharmacological intervention reveal that Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) plays a key role in regulating the levels of plasma low density lipoprotein cholesterol (LDL-C). Here we demonstrate that the compound PF-06446846 inhibits translation of PCSK9 by...
ORGANISM(S): Homo sapiens (Human) 
2017-03-27 | PXD005835 | Pride
Translational stalling Silac Pcsk9 Huh7 cells 
ProteomicsProteomic variation in the oral secretion of Spodoptera exigua and Spodoptera littoralis larvae in response to different food sources
The Spodoptera genus is defined as the pest-rich genus because it contains some of the most destructive lepidopteran crop pests, characterized by a wide host range. During feeding, the caterpillars release small amounts of oral secretion (OS) onto the wounded leaves. This secretion contains herbivo...
ORGANISM(S): Spodoptera littoralis Spodoptera exigua 
2025-01-23 | PXD056472 | Pride
Swath Egyptian cotton leafworm Beet armyworm Dda spectral library Orally secreted proteins 
Sort   by:  
 Page size