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TranscriptomicsGlobal regulation of alternative splicing by adenosine deaminase acting on RNA (ADAR) [RNA-seq]
Alternative mRNA splicing is a major mechanism for gene regulation and transcriptome diversity. Despite the extent of the phenomenon, the regulation and specificity of the splicing machinery are only partially understood. Adenosine-to-inosine (A-to-I) RNA editing of pre-mRNA by ADAR enzymes has been...
ORGANISM(S): Homo sapiens 
2013-06-17 | E-GEOD-47997 | biostudies-arrayexpress
TranscriptomicsGlobal regulation of alternative splicing by adenosine deaminase acting on RNA (ADAR) [expression]
Alternative mRNA splicing is a major mechanism for gene regulation and transcriptome diversity. Despite the extent of the phenomenon, the regulation and specificity of the splicing machinery are only partially understood. Adenosine-to-inosine (A-to-I) RNA editing of pre-mRNA by ADAR enzymes has been...
ORGANISM(S): Homo sapiens 
2013-06-15 | E-GEOD-47945 | biostudies-arrayexpress
TranscriptomicsGlobal regulation of alternative splicing by adenosine deaminase acting on RNA (ADAR)
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2013-06-17 | E-GEOD-47998 | biostudies-arrayexpress
ProteomicsRaw data for manuscript : "Serine synthesis via reversed SHMT2 activity drives glycine depletion and acetaminophen hepatotoxicity in MASLD"
Metabolic dysfunction-associated steatotic liver disease (MASLD) affects one third of the global population. Understanding metabolic pathways involved can provide insights into disease progression and treatment. Untargeted metabolomics of livers from mice with early-stage steatosis uncovered decreas...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2023-12-12 | MSV000093653 | MassIVE
TranscriptomicsAn Integrated Approach to Uncover Drivers of Cancer
We developed a computational framework that integrates chromosomal copy number and gene expression data for detecting aberrations that promote cancer progression. We demonstrate the utility of this framework using a melanoma dataset. Our analysis correctly identified known drivers of melanoma and pr...
ORGANISM(S): Homo sapiens 
2010-12-01 | E-GEOD-23884 | biostudies-arrayexpress
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