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MetabolomicsMetabolome variability for two Mediterranean sponge species of the genus Haliclona: specificity, time, and space

INTRODUCTION: The study of natural variation of metabolites brings valuable information on the physiological state of the organisms as well as their phenotypic traits. In marine organisms, metabolome variability has mostly been addressed through targeted studies on metabolites of...

2021-10-27 | MTBLS638 | MetaboLights
TranscriptomicsThe tinkerbell (tink) mutation identifies the dual-specificity MAPK phosphatase INDOLE-3-BUTYRIC ACID-RESPONSE5 (IBR5) as a novel regulator of organ size in Arabidopsis.
Mitogen-activated dual-specificity MAPK phosphatases are important negative regulators in the MAPK signalling pathways responsible for many essential processes in plants. In a screen for mutants with reduced organ size we have identified a mutation in the active site of the dual-specificity MAPK ph...
ORGANISM(S): Arabidopsis thaliana 
2015-07-30 | E-GEOD-66419 | biostudies-arrayexpress
TranscriptomicsResponsiveness of genes to manipulation of transcription factors in ES cells is associated with chromatin structure and tissue specificity
Background: In addition to determining static states of gene expression (high vs. low), it is important to characterize their dynamic status. For example, genes with H3K27me3 chromatin marks are not only suppressed but also poised for activation. However, the responsiveness of genes to perturbations...
ORGANISM(S): Mus musculus 
2011-02-14 | E-GEOD-22151 | biostudies-arrayexpress
TranscriptomicsResponsiveness of genes to manipulation of transcription factors in ES cells is associated with histone modifications and tissue specificity (1 of 2)
BACKGROUND: In addition to determining static states of gene expression (high vs. low), it is important to characterize their dynamic status. For example, genes with H3K27me3 chromatin marks are not only suppressed but also poised for activation. However, the responsiveness of genes to perturbations...
ORGANISM(S): Mus musculus 
2011-02-11 | E-GEOD-19806 | biostudies-arrayexpress
TranscriptomicsMaize tumors caused by Ustilago maydis require organ-specific genes in host and pathogen
Two-organism transcriptome profiling of infected seedling, adult leaf, and tassel demonstrated that both the host and pathogen exhibit organ-specific expression programs. Phenotypic screening of U. maydis mutants deleted for suites of secreted protein genes and maize growth mutants demonstrated org...
ORGANISM(S): Zea mays 
2010-04-01 | E-GEOD-20130 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat organ of Corti (OC), modiolus (MOD) and stria vascularis (SV) of newborns
The aim of this study was to characterize the basal expression of OC, MOD and SV of newborn rats (3-5 day old) and its changes by short–term cultivation (24 hrs) and mild hypoxia (5 hrs). Three varieties of tissue samples were analyzed (i) Freshly prepared tissue, used as control; (ii) cultures he...
ORGANISM(S): Rattus norvegicus 
2008-06-13 | E-GEOD-5446 | biostudies-arrayexpress
TranscriptomicsResponsiveness of genes to manipulation of transcription factors in ES cells is associated with histone modifications and tissue specificity (2 of 2)
BACKGROUND: In addition to determining static states of gene expression (high vs. low), it is important to characterize their dynamic status. For example, genes with H3K27me3 chromatin marks are not only suppressed but also poised for activation. However, the responsiveness of genes to perturbations...
ORGANISM(S): Mus musculus 
2011-02-11 | E-GEOD-19814 | biostudies-arrayexpress
ProteomicsOrgan Specific Proteomics of Soybean under Flooding and Drought Stresses
Flooding and drought are adverse factors for soybean growth. To obtain better insight into the response mechanism of soybean under flooding and drought stresses, organ specificanalysis was performed using gel-free proteomic technique.
ORGANISM(S): Glycine max 
2017-04-26 | PXD005342 | Pride
Soybean Proteomics Organ specificity Flooding Drought 
ProteomicsTemporary Organ Specific Quantitative Proteomic Analysis of Soybean under Flooding and Drought Stresses
To elucidate the mechanism of soybean responding to flooding and drought, organ specific proteomics and time course proteomics were carried out.
ORGANISM(S): Glycine max 
2015-10-06 | PXD001687 | Pride
Soybean Proteomics Organ specificity Time dependency Flooding Drought 
TranscriptomicsGene regulated by ectopic expression of Sage in the entire Drosophila embryo
FoxA transcription factors play major roles in organ-specific gene expression. How FoxA proteins achieve specificity is unclear, given their broad expression patterns and requirements in multiple cell types. Here, we characterize Sage, a basic helix-loop-helix (bHLH) transcription factor expressed e...
ORGANISM(S): Drosophila melanogaster 
2013-06-06 | E-GEOD-40358 | biostudies-arrayexpress
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