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Targeting adipocyte ESRRA alleviates osteoarthritis via interrupting inter-organelle crosstalk of complement C3-CFD-MAC cascade
Organelle crosstalk plays important functions in metabolic processes and is relevant to immunity, neurodegeneration, and cancer. The permeabilisation and rupture of endolysosomes during stress can induce inflammation and cell death. There is growing evidence that endomembrane damage does not always ...
ORGANISM(S): Homo sapiens (Human) 
2022-10-30 | PXD026045 | Pride
Lysosomes are active sites to integrate cellular metabolism and signal transduction. A collection of proteins enriched at lysosomes mediate these metabolic and signaling functions. Both lysosomal metabolism and lysosomal signaling have been linked with longevity regulation; however, how lysosomes ad...
ORGANISM(S): Caenorhabditis Elegans (ncbitaxon:6239) 
2022-12-15 | MSV000090909 | MassIVE
Lysosomes are active sites to integrate cellular metabolism and signal transduction. A collection of proteins enriched at lysosomes mediate these metabolic and signaling functions. Both lysosomal metabolism and lysosomal signaling have been linked with longevity regulation; however, how lysosomes ad...
ORGANISM(S): Caenorhabditis Elegans (ncbitaxon:6239) 
2023-11-11 | MSV000093375 | MassIVE
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