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ProteomicsCompetitive Profiling of Ligandable Cysteines in Staphylococcus aureus with an Organogold Compound
With the idea of exploiting metal-templated reactions to achieve selective modification of cysteines in proteins for antibacterial applications, an organometallic cyclometalated Au(III) compound was explored in a competitive chemoproteomic approach based on the isoDTB-ABPP (isotopically labelled des...
ORGANISM(S): Staphylococcus aureus 
2022-04-19 | PXD031708 | Pride
Covalent inhibitors Organogold Competitive residue-specific proteomics Antibiotics 
UnknownReactant-induced photoactivation of in situ generated organogold intermediates leading to alkynylated indoles via Csp2-Csp cross-coupling.
Not available
S-EPMC9051093 | biostudies-literature
UnknownAn Organogold Compound as Potential Antimicrobial Agent against Drug-Resistant Bacteria: Initial Mechanistic Insights.
Not available
S-EPMC8518660 | biostudies-literature
UnknownSynthesis of apoptosis-inducing iminophosphorane organogold(III) complexes and study of their interactions with biomolecular targets.
Not available
S-EPMC2765490 | biostudies-literature
UnknownNMR spectroscopy studies of electronic effects and equilibrium in the organogold-to-boron transmetalation reaction and studies towards its application to the alkoxyboration addition of boron-oxygen σ bonds to alkynes.
Not available
S-EPMC6195222 | biostudies-literature
ProteomicsSelective Arylation of Selenocysteine of Thioredoxin Reductase 1 by an Organogold Compound: Expanding the Tool-Box of Metal-Templated Reactions in Cancer Cells - profiling
Cyclometalated gold(III) complexes have been reported to template C-S cross-coupling reactions in a biological environment and acting as modifies of cysteine residues. To broaden the scope of organogold complexes for covalent protein post-translational modification in cancer cells, an oxime-containi...
ORGANISM(S): Homo sapiens (Human) 
2025-04-22 | PXD044966 | Pride
Arylation ∙ cancer ∙ chemoproteomics ∙ gold ∙ metals in medicine ∙ selenoprotein ∙ thioredoxin reductase 1 
ProteomicsSelective Arylation of Selenocysteine of Thioredoxin Reductase 1 by an Organogold Compound: Expanding the Tool-Box of Metal-Templated Reactions in Cancer Cells – pull-down
Cyclometalated gold(III) complexes have been reported to template C-S cross-coupling reactions in a biological environment and acting as modifies of cysteine residues. To broaden the scope of organogold complexes for covalent protein post-translational modification in cancer cells, an oxime-containi...
ORGANISM(S): Homo sapiens (Human) 
2025-04-22 | PXD044971 | Pride
Arylation ∙ cancer ∙ chemoproteomics ∙ gold ∙ metals in medicine ∙ selenoprotein ∙ thioredoxin reductase 1 
UnknownCancer cell-selective modulation of mitochondrial respiration and metabolism by potent organogold(iii) dithiocarbamates.
Not available
S-EPMC8162438 | biostudies-literature
UnknownDinuclear gold-silver resting states may explain silver effects in gold(I)-catalysis.
Not available
S-EPMC2913295 | biostudies-literature
UnknownProtein Recognition of Gold-Based Drugs: 3D Structure of the Complex Formed When Lysozyme Reacts with Aubipy(c.).
Not available
S-EPMC4190628 | biostudies-literature
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