Sort   by:  
 Page size 
TranscriptomicsTranscription profiling of brains from wild type and beta4 nicotinic acetylcholine receptor (nAChR) subunit deficient mice to identify genes that might be related to beta4-containing nAChRs activity
Studies using mice with beta4 nicotinic acetylcholine receptor (nAChR) subunit deficiency (beta4-/- mice) helped reveal the roles of this subunit in bradycardiac response to vagal stimulation, nicotine-induced seizure activity and anxiety. In order to identify genes that might be related to beta4-co...
ORGANISM(S): Mus musculus 
2007-11-27 | E-GEOD-5320 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse brains following nicotine-induced seizures
Nicotine, acting through the neuronal nicotinic acetylcholine receptors (nAChR), can induce seizures in mice. We aimed to study brain transcriptional response to seizure and to identify genes whose expression is altered after nicotine-induced seizures. Whole brains of untreated mice were compared to...
ORGANISM(S): Mus musculus 
2008-04-09 | E-GEOD-6614 | biostudies-arrayexpress
TranscriptomicsThe effects of aging vs. alpha7 nAChR subunit deficiency on the mouse brain transcriptome
Aging is accompanied by expression changes in multiple genes and the brain is one of the tissues most vulnerable to aging. Since the alpha7 nicotinic acetylcholine receptor (nAChR) subunit has been associated with neurodevelopmental disorders and cognitive decline during aging, we hypothesized that ...
ORGANISM(S): Mus musculus 
2011-01-01 | E-GEOD-20411 | biostudies-arrayexpress
Sort   by:  
 Page size