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TranscriptomicsRNA-seq of definitive endoderm differentiation of human embryonic stem cells in early G1 phase of the cell cycle
The experiment was designed to investigate transcriptional dynamics during definitive endoderm differentiation of human embryonic stem cells (hESCs) in early G1 phase of the cell cycle. For this, the FUCCI system was used to sort hESCs in Early G1 (EG1). Samples were taken at 0h (hESCs), 12h, 24h, 3...
ORGANISM(S): Homo sapiens 
2020-09-07 | E-MTAB-9194 | biostudies-arrayexpress
TranscriptomicsBRACHYURY knockdown in differentiating hESCs
Transcriptional profiling of H9 hESCs (wild type and BRACHYURY shRNA knockdown) differentiated for 36h or 72h in chemically-defined culture media supplemented with FGF2, LY294002 and either BMP4 or ActivinA.
ORGANISM(S): Homo sapiens 
2015-05-19 | E-MTAB-2912 | biostudies-arrayexpress
TranscriptomicsActivin/Nodal-dependent N6-methyladenosine (m6A) deposition in human pluripotent stem cells
This experiment was designed to probe the function of Activin/Nodal signalling in the deposition of m6A in human pluripotent stem cells (hPSCs). hPSCs were cultured in presence of Activin or subjected to short-term inhibition of Activin/Nodal signalling for 2h using the receptor antagonist SB-431542...
ORGANISM(S): Homo sapiens 
2017-12-26 | E-MTAB-5229 | biostudies-arrayexpress
TranscriptomicsRNA-seq of WTAP knockdown human pluripotent stem cells during the exit from pluripotency induced by Activin/Nodal inhibition
This experiment was designed to monitor the gene expression changes induced by the knockdown of WTAP in human pluripotent stem cells (hPSCs) during the exit from pluripotency induced by the inhibition of Activin/Nodal signalling. hPSCs carrying a tetracycline-inducible short hairpin RNA (shRNA) agai...
ORGANISM(S): Homo sapiens 
2018-01-04 | E-MTAB-5230 | biostudies-arrayexpress
Genomicsena-DATASET-UCL-ICH-25-11-2015-12:32:35:398-26 - samples
Description not provided
EGAD00001001687 | EGA
GenomicsTelomerase activation by genomic rearrangements in high-risk neuroblastoma
Neuroblastoma is a malignant pediatric tumor of the sympathetic nervous system1. Roughly half of these tumors regress spontaneously or are cured by limited therapy. By contrast, high-risk neuroblastomas have an unfavorable clinical course despite intensive multimodal treatment, and their molecular b...
EGAS00001001308 | EGA
GenomicsDAC University Hospital Cologne
Data Access Committee EGAC00001000361
EGAC00001000361 | EGA
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