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MetabolomicsSystems acclimation to osmotic stress in zygnematophyte cells

Zygnematophytes are the closest algal relatives of land plants. They hold key information to infer how the earliest land plants overcame the barrage of terrestrial stressors, prime of which is osmotic stress. Here, we applied two osmotic stressors on a unicellular and a multicellular representati...

2025-08-12 | MTBLS12267 | MetaboLights
MetabolomicsCDK4/6 inhibitor-mediated cell overgrowth triggers an osmotic stress response and chronic p38MAPK activation to promote long-term cell cycle arrest

Cell size and the cell cycle are intrinsically coupled and abnormal increases in cell size are associated with senescence and permanent cell cycle arrest. The mechanism by which overgrowth primes cells to withdraw from the cell cycle remains unknown. We investigate this here using CDK4/6 inhibito...

2025-10-24 | MTBLS5868 | MetaboLights
MetabolomicsCell overgrowth potentiates osmotic and replication stresses to promote p38/p53/p21-dependent senescence
Abnormal increases in cell size are associated with senescence and cell cycle exit. The mechanisms by which overgrowth primes cells to withdraw from the cell cycle remain unknown. We address this question using CDK4/6 inhibitors, which arrest cells in G0/G1 and are licensed to treat advanced HR+/HER...
2025-10-24 | MTBLS8698 | MetaboLights
MetabolomicsThe circadian clock of Populus affects physiological, transcriptional and metabolomic responses to osmotic and ionic components of salt stress

The circadian oscillator is an innate timing mechanism present in most organisms, including plants. In this study, Populus tremula × P. tremuloides (Populus) trees with reduced expression of circadian clock components were exposed to gradually increa...

2025-10-02 | MTBLS9552 | MetaboLights
TranscriptomicsOsmotic stress on yeast S. cerevisiae
mRNA amount (RA) and Transcription rate (TR) analysis of W303-1a (wt) and hog1 mutant yeast strains growing in exponential phase in YPD subjected to osmotic stress This SuperSeries is composed of the following subset Series: GSE13096: Transcription rate analysis of wild type strain subjected to osm...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-19 | E-GEOD-13100 | biostudies-arrayexpress
TranscriptomicssmRNA under high osmotic stress
To identifiy osmotic stress responsive smRNAs, we used a deep-sequencing technique to profile small RNA populations in leaf and root tissues of plants under high osmotic stress and control conditions. We treated 30day-old plants with high osmotic stress and sampled leaves and roots from the same pla...
ORGANISM(S): Arabidopsis thaliana 
2012-09-19 | E-GEOD-36560 | biostudies-arrayexpress
TranscriptomicsRNAseq of temperature and osmotic stress on detached root of Arabidopsis thaliana col-0 and snrk2.2/2.3
Examine the transcriptomic landscape induced by warm temperature and osmotic stress and its dependency on ABA in Arabidopsis detached roots.
ORGANISM(S): Arabidopsis thaliana 
2025-05-21 | E-MTAB-15125 | biostudies-arrayexpress
TranscriptomicsmRNA amount analysis of W303 hog1 mutant strain subjected to osmotic stress
mRNA amount (RA) analysis of W303 hog1 mutant yeast strain growing in exponential phase in YPD subjected to osmotic stress Keywords: Time course Transcriptomic analysis of three independent replicates the yeast strain growing in exponential phase. Each time point replicate has been hybridized on a ...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-19 | E-GEOD-13099 | biostudies-arrayexpress
TranscriptomicsmRNA amount analysis of wild type strain subjected to osmotic stress
mRNA amount (RA) analysis of W303-1a yeast strain growing in exponential phase in YPD subjected to osmotic stress Keywords: time course Transcriptomic analysis of three independent replicates the yeast strain growing in exponential phase. Each time point replicate has been hybridized on a different...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-19 | E-GEOD-13097 | biostudies-arrayexpress
TranscriptomicsTranscription rate analysis of W303 hog1 mutant strain subjected to osmotic stress
Transcription rate (TR) analysis of W303 hog1 mutant yeast strain growing in exponential phase in YPD subjected to osmotic stress Keywords: Time course Transcription rate analysis by means of GRO of three independent replicates the yeast strain growing in exponential phase. Each time point replicat...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-19 | E-GEOD-13098 | biostudies-arrayexpress
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