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TranscriptomicsGlobal changes in gene expression in dermal fibroblasts with in vivo and in vitro deletion of the RBP-Jk gene
It is currently unclear whether tissue changes surrounding multifocal epithelial tumors are a cause or consequence of cancer. Here, we provide evidence that loss of mesenchymal Notch/CSL signaling causes tissue alterations, including stromal atrophy and inflammation, which precede and are potent tri...
ORGANISM(S): Mus musculus 
2012-06-11 | E-GEOD-36359 | biostudies-arrayexpress
TranscriptomicsA platform of patient-derived tumor xenografts (EOC-xenografts) to recapitulate the clinicopathology and genetic alterations of ovarian cancer
Epithelial ovarian cancer (EOC) is the most lethal gynecological malignancy. On the basis of its histopathology and molecular-genomic changes ovarian cancer has been divided into subtypes, each with distinct biology and outcome. The aim of this study was to develop a panel of patient-derived EOC-xen...
ORGANISM(S): Homo sapiens 
2015-01-07 | E-GEOD-56920 | biostudies-arrayexpress
TranscriptomicsInfluence of organic cultivation on potato transcriptome
Analysis of the transcription profiles in tubers of S. tuberosum L. cv. Ditta grown in two experimental seasons under either conventional or organic crop management.
ORGANISM(S): Solanum tuberosum 
2017-05-11 | E-MTAB-3367 | biostudies-arrayexpress
UnknownComprehensive Gene Expression Analysis to Identify Differences and Similarities between Sex- and Stage-Stratified Melanoma Samples.
Not available
S-EPMC8997401 | biostudies-literature
UnknownNegative control of CSL gene transcription by stress/DNA damage response and p53.
Not available
S-EPMC4957600 | biostudies-literature
UnknownGene and microRNA modulation upon trabectedin treatment in a human intrahepatic cholangiocarcinoma paired patient derived xenograft and cell line.
Not available
S-EPMC5349952 | biostudies-literature
TranscriptomicsmiRNA profiling of mixoid liposarcoma cell lines sensitive and resistant to trabectidin
This investigation aims at identifying differentially expressed miRNA between two cell lines, MLS 402-91 (sensitive to trabectidin) and MLS 402-91/ET (resistant to trabectidin).
ORGANISM(S): Homo sapiens 
2012-06-05 | E-MTAB-695 | biostudies-arrayexpress
UnknownNotch-effector CSL promotes squamous cell carcinoma by repressing histone demethylase KDM6B.
Not available
S-EPMC5983322 | biostudies-literature
UnknownNOTCH1 gene amplification promotes expansion of Cancer Associated Fibroblast populations in human skin.
Not available
S-EPMC7550609 | biostudies-literature
UnknownCells with stemness features are generated from in vitro transformed human fibroblasts.
Not available
S-EPMC6138721 | biostudies-literature
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