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TranscriptomicsExpression profiling of peripheral blood of chronic HCV infection
In the present study, we studied chronic HCV patients who responded to IFN-based therapy as evidenced by absence of HCV RNA at the end of treatment, and focused on two issues that have not received much attention. Firstly, we evaluated whether specific genes or gene expression patterns in blood were...
ORGANISM(S): Homo sapiens 
2014-09-02 | E-GEOD-59312 | biostudies-arrayexpress
TranscriptomicsEarly divergence of Th1 and Th2 transcriptomes involves a small core response and sets of transiently expressed genes
Helper T cells can adopt a number of different phenotypes. We performed microarray-assisted mRNA profiling on antigen-stimulated, TCR transgenic murine splenocytes that were cultured in the presence of cytokines. Transcriptome snapshots of Th cells differentiating into Th1 and Th2 phenotypes were o...
ORGANISM(S): Mus musculus 
2013-03-01 | E-MTAB-1475 | biostudies-arrayexpress
TranscriptomicsSmall hydrophobic protein of human metapneumovirus does not affect virus replication and host gene expression in vitro
In vitro infection experiment with genetically modified human metapneumovirus (HMPV) to study the function of the viral small hydrophobic (SH) protein.
ORGANISM(S): Homo sapiens 
2014-11-23 | E-MTAB-1152 | biostudies-arrayexpress
TranscriptomicsBlood mRNA profiling to support prognosis of disease severity in respiratory syncytial virus infected infants
In this study we investigated whether there exists a genomic signature that can accurately predict the course of a respiratory syncytial virus (RSV) infection in hospitalized young infants. We used early blood microarray transcriptome profiles from 39 infants that were followed until recovery and of...
ORGANISM(S): Homo sapiens 
2016-11-11 | E-MTAB-5195 | biostudies-arrayexpress
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