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xref:PubMed:41102149 (1)

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Low input Hi-C datasets for a diffuse large B-cell lymphoma sample, healthy control human B-cells and mouse embryonic stem cells

In this experiment, we've examined chromatin conformation of OG2 (B6; CBA-Tg(Pou5f1-EGFP)2Mnn/J; stock number 004654) mouse stem cells cultured as described in (Shi et al., 2008), using different amounts of starting cells. We performed a modified in situ Hi-C protocol for 6 samples digested with Mbo...

ORGANISM(S): Mus musculus

2018-11-30 | E-MTAB-5875 | biostudies-arrayexpress

Identification of ETO2-GLIS2 transcriptional targets

Acute megakaryoblastic leukemia (AMKL) is a subtype of leukemia primarily diagnosed in childhood and generally associated with poor prognosis. Genetic alterations found in de novo childhood AMKL include the OTT-MAL fusion, MLL and NUP98 fusions and the recently identified ETO2-GLIS2 fusion that invo...

ORGANISM(S): Homo sapiens

2017-05-05 | E-MTAB-4332 | biostudies-arrayexpress

IGR_MEGAKARYOCYTE_STUDY_TM

The OTT1-MAL fusion oncogene is specifically associated with human infant acute megakaryoblastic leukemia. In a murine model of OTT-MAL expression, leukemic cells expressing OTT-MAL present an aberrant activation of the Notch pathway target genes. IKZF1 was proposed to interact with the Notch signal...

ORGANISM(S): Mus musculus

2013-08-08 | E-MTAB-897 | biostudies-arrayexpress

Identification of c-myc target genes by siRNA

To identify c-myc target genes by siRNA transfection in a lymphoma cell line. Keywords: time series design OCI-Ly10 cells were transfected with c-myc siRNA pool versus control siRNA or buffer for a total of 4 microarrays.

ORGANISM(S): Homo sapiens

2010-05-26 | E-GEOD-7245 | biostudies-arrayexpress

Mutational analysis of the C-terminal gag cleavage sites in human immunodeficiency virus type 1.

Not available

S-EPMC2045408 | biostudies-literature

Gene expression in epithelial and non-epithelial cells of renal origin

We aimed to define epithelial-specific genes in the kidney. In the developing mouse kidney at E12.5 epithelial cells are restricted to the ureteric bud, while mesenchymal cells surrounding the ureteric bud are non-epithelial. The mouse renal epithelial cell line mIMCD-3 was used to represent kidney ...

ORGANISM(S): Mus musculus

2010-09-23 | E-GEOD-24295 | biostudies-arrayexpress

Oms1 associates with cytochrome c oxidase assembly intermediates to stabilize newly synthesized Cox1.

Not available

S-EPMC4865315 | biostudies-literature

Rcf1 Modulates Cytochrome c Oxidase Activity Especially Under Energy-Demanding Conditions.

Not available

S-EPMC6971206 | biostudies-literature

RNAi knock-down of MKL1 in human megakaryocytes derived from cord blood or cytapheresis

Characterize the genes regulated by MKL1/SRF complex in human megakaryocytes (MKs) derived from cord blood or cytapheresis : Using a knock down approach by small interference of MKL1 in MK progenitors, we observed a decrease in the percentage of cells with actin polymerization after adhesion on vari...

ORGANISM(S): Homo sapiens

2009-09-14 | E-TABM-640 | biostudies-arrayexpress

c-MPL provides tumor-targeted T-cell receptor-transgenic T cells with costimulation and cytokine signals.

Not available

S-EPMC5746163 | biostudies-literature

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