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TranscriptomicsIdentification of ETO2-GLIS2 transcriptional targets
Acute megakaryoblastic leukemia (AMKL) is a subtype of leukemia primarily diagnosed in childhood and generally associated with poor prognosis. Genetic alterations found in de novo childhood AMKL include the OTT-MAL fusion, MLL and NUP98 fusions and the recently identified ETO2-GLIS2 fusion that invo...
ORGANISM(S): Homo sapiens 
2017-05-05 | E-MTAB-4332 | biostudies-arrayexpress
UnknownExperimental realization of a Rydberg optical Feshbach resonance in a quantum many-body system.
Not available
S-EPMC5993778 | biostudies-literature
GenomicsIdentification of ETO2-GLIS2 targets by ChIP-sequencing
Acute megakaryoblastic leukemia (AMKL) is a subtype of leukemia primarily diagnosed in childhood and generally associated with poor prognosis. Genetic alterations found in de novo childhood AMKL include the OTT-MAL fusion, MLL and NUP98 fusions and the recently identified ETO2-GLIS2 fusion that invo...
ORGANISM(S): Homo sapiens 
2017-05-22 | E-MTAB-4367 | biostudies-arrayexpress
UnknownCXCR5-Dependent Entry of CD8 T Cells into Rhesus Macaque B-Cell Follicles Achieved through T-Cell Engineering.
Not available
S-EPMC5432868 | biostudies-literature
UnknownPhase I/II study of the antibody-drug conjugate glembatumumab vedotin in patients with advanced melanoma.
Not available
S-EPMC4879709 | biostudies-literature
TranscriptomicsRNAi knock-down of MKL1 in human megakaryocytes derived from cord blood or cytapheresis
Characterize the genes regulated by MKL1/SRF complex in human megakaryocytes (MKs) derived from cord blood or cytapheresis : Using a knock down approach by small interference of MKL1 in MK progenitors, we observed a decrease in the percentage of cells with actin polymerization after adhesion on vari...
ORGANISM(S): Homo sapiens 
2009-09-14 | E-TABM-640 | biostudies-arrayexpress
UnknownTCR triggering transcriptionally downregulates CCR5 expression on rhesus macaque CD4(+) T-cells with no measurable effect on susceptibility to SIV infection.
Not available
S-EPMC3001627 | biostudies-literature
TranscriptomicsBurkitt Lymphoma Pathogenesis and Therapeutic Targets from Structural and Functional Genomics
Burkitt lymphoma (BL) can often be cured by intensive chemotherapy, but the toxicity of such therapy precludes its use in the elderly and in patients with endemic BL (eBL) in developing countries, necessitating new strategies. The normal germinal center B cell is the presumed cell of origin for both...
ORGANISM(S): Homo sapiens 
2012-08-16 | E-GEOD-35163 | biostudies-arrayexpress
UnknownSOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death.
Not available
S-EPMC10842433 | biostudies-literature
UnknownThe Short Isoform of BRD4 Promotes HIV-1 Latency by Engaging Repressive SWI/SNF Chromatin-Remodeling Complexes.
Not available
S-EPMC5610089 | biostudies-literature
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